PGF (placental growth factor)

2003-02-01  

Identity

HGNC
PGF
LOCATION
14q24.3
LOCUSID
5228
ALIAS
D12S1900,PGFL,PIGF,PLGF,PlGF-2,SHGC-10760

Other Information

Locus ID:

NCBI: 5228
MIM: 601121
HGNC: 8893
Ensembl: ENSG00000119630

Variants:

dbSNP: 5228
ClinVar: 5228
TCGA: ENSG00000119630
COSMIC: PGF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000119630ENST00000238607G3XA84
ENSG00000119630ENST00000405431P49763
ENSG00000119630ENST00000553716P49763
ENSG00000119630ENST00000555567P49763
ENSG00000119630ENST00000555567Q53XY6

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Focal adhesionKEGGko04510
Focal adhesionKEGGhsa04510
Pathways in cancerKEGGhsa05200
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151
Ras signaling pathwayKEGGhsa04014
Rap1 signaling pathwayKEGGhsa04015
Rap1 signaling pathwayKEGGko04015
Signal TransductionREACTOMER-HSA-162582
Signaling by VEGFREACTOMER-HSA-194138
VEGF ligand-receptor interactionsREACTOMER-HSA-194313
VEGF binds to VEGFR leading to receptor dimerizationREACTOMER-HSA-195399

References

Pubmed IDYearTitleCitations
378780352024Expression of placental growth factor, neuropilin-1, and neuropilin-2 in primary pterygium tissue.0
381667392024Predictive value of maternal serum placental growth factor levels for discordant fetal growth in twins: a retrospective cohort study.0
382175982024Serum Placental Growth Factor as a Marker of Cerebrovascular Disease Burden in Alzheimer's Disease.0
382472742024Assessment of serum levels and placental bed tissue expression of IGF-1, bFGF, and PLGF in patients with placenta previa complicated with placenta accreta spectrum disorders.0
378780352024Expression of placental growth factor, neuropilin-1, and neuropilin-2 in primary pterygium tissue.0
381667392024Predictive value of maternal serum placental growth factor levels for discordant fetal growth in twins: a retrospective cohort study.0
382175982024Serum Placental Growth Factor as a Marker of Cerebrovascular Disease Burden in Alzheimer's Disease.0
382472742024Assessment of serum levels and placental bed tissue expression of IGF-1, bFGF, and PLGF in patients with placenta previa complicated with placenta accreta spectrum disorders.0
361930312023Screening of candidate genes at GLC3B and GLC3C loci in Chinese primary congenital glaucoma patients with targeted next generation sequencing.0
369903082023Accuracy of placental growth factor alone or in combination with soluble fms-like tyrosine kinase-1 or maternal factors in detecting preeclampsia in asymptomatic women in the second and third trimesters: a systematic review and meta-analysis.2
371683132023Changes in concentrations of melatonin, PlGF, and cytokines in women with preeclampsia.1
375120442023sFLT1, PlGF, the sFLT1/PlGF Ratio and Their Association with Pre-Eclampsia in Twin Pregnancies-A Review of the Literature.1
376792522023The cytokine trio - visfatin, placental growth factor and fractalkine - and their role in myocardial infarction with non-obstructive coronary arteries (MINOCA).4
377124212023Maternal PlGF and umbilical Dopplers predict pregnancy outcomes at diagnosis of early-onset fetal growth restriction.2
377879822023Causal association between placental growth factor and coronary heart disease: a Mendelian randomization study.1

Citation

Dessen P

PGF (placental growth factor)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41696