Identity
HGNC
LOCATION
Xq21.1
LOCUSID
ALIAS
HEL-S-68p,MIG10,PGKA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5230
MIM: 311800
HGNC: 8896
Ensembl: ENSG00000102144
Variants:
dbSNP: 5230
ClinVar: 5230
TCGA: ENSG00000102144
COSMIC: PGK1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000102144 | ENST00000373316 | P00558 |
| ENSG00000102144 | ENST00000373316 | V9HWF4 |
| ENSG00000102144 | ENST00000644362 | P00558 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA450163 | lamivudine | Chemical | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38110073 | 2024 | Upregulation of mitochondrial PGK1 by ROS-TBC1D15 pathway promotes neuronal death after oxygen-glucose deprivation/reoxygenation injury. | 0 |
| 38163864 | 2024 | The oncogenic role and regulatory mechanism of PGK1 in human non-small cell lung cancer. | 2 |
| 38247832 | 2024 | RNA Binding Protein PTBP1 Promotes the Metastasis of Gastric Cancer by Stabilizing PGK1 mRNA. | 0 |
| 38402202 | 2024 | PRMT1-mediated PGK1 arginine methylation promotes colorectal cancer glycolysis and tumorigenesis. | 0 |
| 38459513 | 2024 | CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation. | 0 |
| 38471523 | 2024 | PUM1 and PGK1 are Favorable Housekeeping Genes over Established Biodosimetry-related Housekeeping Genes such as HPRT1, ITFG1, DPM1, MRPS5, 18S rRNA and Others after Radiation Exposure. | 0 |
| 38110073 | 2024 | Upregulation of mitochondrial PGK1 by ROS-TBC1D15 pathway promotes neuronal death after oxygen-glucose deprivation/reoxygenation injury. | 0 |
| 38163864 | 2024 | The oncogenic role and regulatory mechanism of PGK1 in human non-small cell lung cancer. | 2 |
| 38247832 | 2024 | RNA Binding Protein PTBP1 Promotes the Metastasis of Gastric Cancer by Stabilizing PGK1 mRNA. | 0 |
| 38402202 | 2024 | PRMT1-mediated PGK1 arginine methylation promotes colorectal cancer glycolysis and tumorigenesis. | 0 |
| 38459513 | 2024 | CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation. | 0 |
| 38471523 | 2024 | PUM1 and PGK1 are Favorable Housekeeping Genes over Established Biodosimetry-related Housekeeping Genes such as HPRT1, ITFG1, DPM1, MRPS5, 18S rRNA and Others after Radiation Exposure. | 0 |
| 36171455 | 2023 | N(6)-methyladenosine reader YTHDF3 contributes to the aerobic glycolysis of osteosarcoma through stabilizing PGK1 stability. | 10 |
| 36841032 | 2023 | PGK1 modulates balance between pro- and anti-inflammatory cytokines by interacting with ITI-H4. | 2 |
| 36949536 | 2023 | Circular RNA circHMCU promotes breast tumorigenesis through miR-4458/PGK1 regulatory cascade. | 1 |
Citation
Dessen P
PGK1 (phosphoglycerate kinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41697/pgk1
