PIK3C2G (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma)

2003-06-01  

Identity

HGNC
PIK3C2G
LOCATION
12p12.3
LOCUSID
5288
ALIAS
PI3K-C2-gamma,PI3K-C2GAMMA
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5288
MIM: 609001
HGNC: 8973
Ensembl: ENSG00000139144

Variants:

dbSNP: 5288
ClinVar: 5288
TCGA: ENSG00000139144
COSMIC: PIK3C2G

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139144ENST00000433979O75747
ENSG00000139144ENST00000535651F5H7Y7
ENSG00000139144ENST00000536967A0A087WV31
ENSG00000139144ENST00000538779F5H369
ENSG00000139144ENST00000546003F5GWG6

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Inositol phosphate metabolismKEGGko00562
Phosphatidylinositol signaling systemKEGGko04070
Inositol phosphate metabolismKEGGhsa00562
Phosphatidylinositol signaling systemKEGGhsa04070
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
PI MetabolismREACTOMER-HSA-1483255
Synthesis of PIPs at the Golgi membraneREACTOMER-HSA-1660514
Synthesis of PIPs at the plasma membraneREACTOMER-HSA-1660499

References

Pubmed IDYearTitleCitations
333873692021The molecular mechanisms mediating class II PI 3-kinase function in cell physiology.6
336662172021Class II phosphatidylinositol 3-kinase isoforms in vesicular trafficking.6
333873692021The molecular mechanisms mediating class II PI 3-kinase function in cell physiology.6
336662172021Class II phosphatidylinositol 3-kinase isoforms in vesicular trafficking.6
249836632015Development of first lead structures for phosphoinositide 3-kinase-C2γ inhibitors.10
249836632015Development of first lead structures for phosphoinositide 3-kinase-C2γ inhibitors.10
206026152010Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?3
206026152010Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?3
189961022009Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.13
189961022009Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.13
178937072008An association screen of myelin-related genes implicates the chromosome 22q11 PIK4CA gene in schizophrenia.56
179914252008Association of the PIK3C2G gene polymorphisms with type 2 DM in a Japanese population.11
179914252008Association of the PIK3C2G gene polymorphisms with type 2 DM in a Japanese population.11
178937072008An association screen of myelin-related genes implicates the chromosome 22q11 PIK4CA gene in schizophrenia.56
179914252008Association of the PIK3C2G gene polymorphisms with type 2 DM in a Japanese population.11

Citation

Dessen P

PIK3C2G (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41713/favicon/meetings/