LMO3 (LIM domain only 3)

2004-05-01  

Identity

HGNC
LMO3
LOCATION
12p12.3
LOCUSID
55885
ALIAS
RBTN3,RBTNL2,RHOM3,Rhom-3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55885
MIM: 180386
HGNC: 6643
Ensembl: ENSG00000048540

Variants:

dbSNP: 55885
ClinVar: 55885
TCGA: ENSG00000048540
COSMIC: LMO3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000048540ENST00000261169Q8TAP4
ENSG00000048540ENST00000320122Q8TAP4
ENSG00000048540ENST00000320122A0A024RAT1
ENSG00000048540ENST00000354662Q8TAP4
ENSG00000048540ENST00000354662A0A024RAT1
ENSG00000048540ENST00000396205F6TDU8
ENSG00000048540ENST00000424192C9JE61
ENSG00000048540ENST00000441439Q8TAP4
ENSG00000048540ENST00000441439A0A024RAT1
ENSG00000048540ENST00000447609Q8TAP4
ENSG00000048540ENST00000447609A0A024RAT1
ENSG00000048540ENST00000453727Q05D86
ENSG00000048540ENST00000534946Q8TAP4
ENSG00000048540ENST00000534946A0A024RAT1
ENSG00000048540ENST00000535535Q8TAP4
ENSG00000048540ENST00000535535A0A024RAT1
ENSG00000048540ENST00000536172Q05D86
ENSG00000048540ENST00000537304Q8TAP4
ENSG00000048540ENST00000537304A0A024RAT1
ENSG00000048540ENST00000537757F5H3S4
ENSG00000048540ENST00000538020F5H4K9
ENSG00000048540ENST00000538051F5H2N9
ENSG00000048540ENST00000539232Q05D86
ENSG00000048540ENST00000539534F5H3S4
ENSG00000048540ENST00000540445Q8TAP4
ENSG00000048540ENST00000540590F5H4T0
ENSG00000048540ENST00000540848Q8TAP4
ENSG00000048540ENST00000540848A0A024RAT1
ENSG00000048540ENST00000541295Q8TAP4
ENSG00000048540ENST00000541589Q05D86
ENSG00000048540ENST00000541764F5H655
ENSG00000048540ENST00000541846Q8TAP4
ENSG00000048540ENST00000541846A0A024RAT1
ENSG00000048540ENST00000544754F6TDU8
ENSG00000048540ENST00000545436F5GZR3
ENSG00000048540ENST00000546279F5GYZ6
ENSG00000048540ENST00000546281F5H3S4
ENSG00000048540ENST00000616247A0A087WYA2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
364267312023Circ_0007385 promotes the proliferation and inhibits the apoptosis of non-small cell lung cancer cells via miR-337-3p-dependent regulation of LMO3.0
364267312023Circ_0007385 promotes the proliferation and inhibits the apoptosis of non-small cell lung cancer cells via miR-337-3p-dependent regulation of LMO3.0
351657912022Transcriptomic analysis and biological evaluation reveals that LMO3 regulates the osteogenic differentiation of human adipose derived stem cells via PI3K/Akt signaling pathway.2
364138522022Hyperglycemia affects neuronal differentiation and Nestin, FOXO1, and LMO3 mRNA expression of human Wharton's jelly mesenchymal stem cells of children from diabetic mothers.1
351657912022Transcriptomic analysis and biological evaluation reveals that LMO3 regulates the osteogenic differentiation of human adipose derived stem cells via PI3K/Akt signaling pathway.2
364138522022Hyperglycemia affects neuronal differentiation and Nestin, FOXO1, and LMO3 mRNA expression of human Wharton's jelly mesenchymal stem cells of children from diabetic mothers.1
340180162021LMO3 reprograms visceral adipocyte metabolism during obesity.4
340180162021LMO3 reprograms visceral adipocyte metabolism during obesity.4
314888732019Newly identified LMO3-BORCS5 fusion oncogene in Ewing sarcoma at relapse is a driver of tumor progression.5
316465712019MicroRNA-381 inhibits lung adenocarcinoma cell biological progression by directly targeting LMO3 through regulation of the PI3K/Akt signaling pathway and epithelial-to-mesenchymal transition.9
314888732019Newly identified LMO3-BORCS5 fusion oncogene in Ewing sarcoma at relapse is a driver of tumor progression.5
316465712019MicroRNA-381 inhibits lung adenocarcinoma cell biological progression by directly targeting LMO3 through regulation of the PI3K/Akt signaling pathway and epithelial-to-mesenchymal transition.9
294366062018LMO3 promotes gastric cancer cell invasion and proliferation through Akt-mTOR and Akt-GSK3β signaling.10
302190642018LMO3 promotes hepatocellular carcinoma invasion, metastasis and anoikis inhibition by directly interacting with LATS1 and suppressing Hippo signaling.21
294366062018LMO3 promotes gastric cancer cell invasion and proliferation through Akt-mTOR and Akt-GSK3β signaling.10

Citation

Dessen P

LMO3 (LIM domain only 3)

Atlas Genet Cytogenet Oncol Haematol. 2004-05-01

Online version: http://atlasgeneticsoncology.org/gene/418/teaching-explorer/gene-fusions/?id=418