Identity
HGNC
LOCATION
2p23.2
LOCUSID
ALIAS
HEL-S-80p,MP,NSLH2,PP-1B,PP1B,PP1beta,PP1c,PPP1CD,PPP1beta
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5500
MIM: 600590
HGNC: 9282
Ensembl: ENSG00000213639
Variants:
dbSNP: 5500
ClinVar: 5500
TCGA: ENSG00000213639
COSMIC: PPP1CB
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33491856 | 2021 | Noonan syndrome with loose anagen hair with variants in the PPP1CB gene: First familial case reported. | 4 |
| 34125004 | 2021 | The expression and clinical prognostic value of protein phosphatase 1 catalytic subunit beta in pancreatic cancer. | 0 |
| 34425033 | 2021 | PP-1β and PP-2Aα modulate cAMP response element-binding protein (CREB) functions in aging control and stress response through de-regulation of αB-crystallin gene and p300-p53 signaling axis. | 6 |
| 33491856 | 2021 | Noonan syndrome with loose anagen hair with variants in the PPP1CB gene: First familial case reported. | 4 |
| 34125004 | 2021 | The expression and clinical prognostic value of protein phosphatase 1 catalytic subunit beta in pancreatic cancer. | 0 |
| 34425033 | 2021 | PP-1β and PP-2Aα modulate cAMP response element-binding protein (CREB) functions in aging control and stress response through de-regulation of αB-crystallin gene and p300-p53 signaling axis. | 6 |
| 31108500 | 2020 | Activating MRAS mutations cause Noonan syndrome associated with hypertrophic cardiomyopathy. | 21 |
| 32266926 | 2020 | Integrative genomics analysis of eQTL and GWAS summary data identifies PPP1CB as a novel bone mineral density risk genes. | 0 |
| 32476286 | 2020 | A case report of Noonan syndrome-like disorder with loose anagen hair 2 treated with recombinant human growth hormone. | 1 |
| 31108500 | 2020 | Activating MRAS mutations cause Noonan syndrome associated with hypertrophic cardiomyopathy. | 21 |
| 32266926 | 2020 | Integrative genomics analysis of eQTL and GWAS summary data identifies PPP1CB as a novel bone mineral density risk genes. | 0 |
| 32476286 | 2020 | A case report of Noonan syndrome-like disorder with loose anagen hair 2 treated with recombinant human growth hormone. | 1 |
| 30368668 | 2019 | Delineation of LZTR1 mutation-positive patients with Noonan syndrome and identification of LZTR1 binding to RAF1-PPP1CB complexes. | 34 |
| 31315927 | 2019 | TIMAP inhibits endothelial myosin light chain phosphatase by competing with MYPT1 for the catalytic protein phosphatase 1 subunit PP1cβ. | 6 |
| 31323436 | 2019 | HOXA2 activity regulation by cytoplasmic relocation, protein stabilization and post-translational modification. | 2 |
Citation
Dessen P
PPP1CB (protein phosphatase 1 catalytic subunit beta)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41805/ppp1cb
