Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5537
MIM: 612725
HGNC: 9323
Ensembl: ENSG00000119414
Variants:
dbSNP: 5537
ClinVar: 5537
TCGA: ENSG00000119414
COSMIC: PPP6C
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38745265 | 2024 | M6A-induced transcription factor IRF5 contributes to the progression of cervical cancer by upregulating PPP6C. | 0 |
| 38745265 | 2024 | M6A-induced transcription factor IRF5 contributes to the progression of cervical cancer by upregulating PPP6C. | 0 |
| 36071040 | 2022 | PP6 negatively modulates LUBAC-mediated M1-ubiquitination of RIPK1 and c-FLIP(L) to promote TNFα-mediated cell death. | 5 |
| 36071040 | 2022 | PP6 negatively modulates LUBAC-mediated M1-ubiquitination of RIPK1 and c-FLIP(L) to promote TNFα-mediated cell death. | 5 |
| 33789117 | 2021 | PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK. | 17 |
| 34314486 | 2021 | Protein phosphatase 6 promotes neurite outgrowth by promoting mTORC2 activity in N2a cells. | 3 |
| 34587164 | 2021 | MiR-20a-5p functions as a potent tumor suppressor by targeting PPP6C in acute myeloid leukemia. | 5 |
| 33789117 | 2021 | PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK. | 17 |
| 34314486 | 2021 | Protein phosphatase 6 promotes neurite outgrowth by promoting mTORC2 activity in N2a cells. | 3 |
| 34587164 | 2021 | MiR-20a-5p functions as a potent tumor suppressor by targeting PPP6C in acute myeloid leukemia. | 5 |
| 32474700 | 2020 | Dephosphorylation of cGAS by PPP6C impairs its substrate binding activity and innate antiviral response. | 25 |
| 32753499 | 2020 | PPP6C Negatively Regulates STING-Dependent Innate Immune Responses. | 19 |
| 32474700 | 2020 | Dephosphorylation of cGAS by PPP6C impairs its substrate binding activity and innate antiviral response. | 25 |
| 32753499 | 2020 | PPP6C Negatively Regulates STING-Dependent Innate Immune Responses. | 19 |
| 29539411 | 2018 | A PP6-ASK3 Module Coordinates the Bidirectional Cell Volume Regulation under Osmotic Stress. | 15 |
Citation
Dessen P
PPP6C (protein phosphatase 6 catalytic subunit)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41826/ppp6c
