PTP4A1 (protein tyrosine phosphatase 4A1)

2003-02-01  

Identity

HGNC
LOCATION
6q12
LOCUSID
ALIAS
HH72,PRL-1,PRL1,PTP(CAAX1),PTPCAAX1
FUSION GENES

Other Information

Locus ID:

NCBI: 7803
MIM: 601585
HGNC: 9634
Ensembl: ENSG00000112245

Variants:

dbSNP: 7803
ClinVar: 7803
TCGA: ENSG00000112245
COSMIC: PTP4A1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112245ENST00000626021Q93096
ENSG00000112245ENST00000626021A0A024R8J2
ENSG00000112245ENST00000627002A0A0D9SGK2
ENSG00000112245ENST00000639568A0A3B3ISR8
ENSG00000112245ENST00000648894Q93096
ENSG00000112245ENST00000648894A0A024R8J2
ENSG00000112245ENST00000672924A0A024R8J2
ENSG00000112245ENST00000673199A0A024R8J2

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
365349752023Endothelial PTP4A1 mitigates vascular inflammation via USF1/A20 axis-mediated NF-κB inactivation.4
365349752023Endothelial PTP4A1 mitigates vascular inflammation via USF1/A20 axis-mediated NF-κB inactivation.4
351379282022GINS2 regulates the proliferation and apoptosis of colon cancer cells through PTP4A1.5
351379282022GINS2 regulates the proliferation and apoptosis of colon cancer cells through PTP4A1.5
335028232021LncRNA NEAT1 promotes cell proliferation, migration, and invasion via the miR-186-5p/PTP4A1 axis in cholangiocarcinoma.7
335028232021LncRNA NEAT1 promotes cell proliferation, migration, and invasion via the miR-186-5p/PTP4A1 axis in cholangiocarcinoma.7
293452912018MicroRNA-1271 functions as a metastasis and epithelial-mesenchymal transition inhibitor in human HCC by targeting the PTP4A1/c-Src axis.16
294871652018Phosphatase of regenerating liver maintains cellular magnesium homeostasis.7
304626252018miR-339-5p Increases Radiosensitivity of Lung Cancer Cells by Targeting Phosphatases of Regenerating Liver-1 (PRL-1).10
305151562018Phosphatase of Regenerating Liver-1 (PRL-1) Regulates Actin Dynamics During Immunological Synapse Assembly and T Cell Effector Function.5
293452912018MicroRNA-1271 functions as a metastasis and epithelial-mesenchymal transition inhibitor in human HCC by targeting the PTP4A1/c-Src axis.16
294871652018Phosphatase of regenerating liver maintains cellular magnesium homeostasis.7
304626252018miR-339-5p Increases Radiosensitivity of Lung Cancer Cells by Targeting Phosphatases of Regenerating Liver-1 (PRL-1).10
305151562018Phosphatase of Regenerating Liver-1 (PRL-1) Regulates Actin Dynamics During Immunological Synapse Assembly and T Cell Effector Function.5
290579342017PTP4A1 promotes TGFβ signaling and fibrosis in systemic sclerosis.25

Citation

Dessen P

PTP4A1 (protein tyrosine phosphatase 4A1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41906/ptp4a1