Identity
HGNC
LOCATION
7q31.32
LOCUSID
ALIAS
HPTPZ,HPTPzeta,PTP-ZETA,PTP18,PTPRZ,PTPZ,R-PTP-zeta-2,RPTPB,RPTPbeta,phosphacan
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5803
MIM: 176891
HGNC: 9685
Ensembl: ENSG00000106278
Variants:
dbSNP: 5803
ClinVar: 5803
TCGA: ENSG00000106278
COSMIC: PTPRZ1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Epithelial cell signaling in Helicobacter pylori infection | KEGG | ko05120 |
| Epithelial cell signaling in Helicobacter pylori infection | KEGG | hsa05120 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37543361 | 2023 | Brain-specific glycosylation enzyme GnT-IX maintains levels of protein tyrosine phosphatase receptor PTPRZ, thereby mediating glioma growth. | 0 |
| 37543361 | 2023 | Brain-specific glycosylation enzyme GnT-IX maintains levels of protein tyrosine phosphatase receptor PTPRZ, thereby mediating glioma growth. | 0 |
| 35457233 | 2022 | Protein Tyrosine Phosphatase Receptor Type Z in Central Nervous System Disease. | 6 |
| 35883571 | 2022 | The Glycoprotein M6a Is Associated with Invasiveness and Radioresistance of Glioblastoma Stem Cells. | 5 |
| 35457233 | 2022 | Protein Tyrosine Phosphatase Receptor Type Z in Central Nervous System Disease. | 6 |
| 35883571 | 2022 | The Glycoprotein M6a Is Associated with Invasiveness and Radioresistance of Glioblastoma Stem Cells. | 5 |
| 33645009 | 2021 | High-sensitive clinical diagnostic method for PTPRZ1-MET and the characteristic protein structure contributing to ligand-independent MET activation. | 5 |
| 33645009 | 2021 | High-sensitive clinical diagnostic method for PTPRZ1-MET and the characteristic protein structure contributing to ligand-independent MET activation. | 5 |
| 31381204 | 2020 | A novel PTPRZ1-ETV1 fusion in gliomas. | 10 |
| 31381204 | 2020 | A novel PTPRZ1-ETV1 fusion in gliomas. | 10 |
| 31364003 | 2019 | MiR-1261/circ-PTPRZ1/PAK1 pathway regulates glioma cell growth and invasion. | 6 |
| 31364003 | 2019 | MiR-1261/circ-PTPRZ1/PAK1 pathway regulates glioma cell growth and invasion. | 6 |
| 29651006 | 2018 | Cyclin-dependent kinase 5 mediates pleiotrophin-induced endothelial cell migration. | 12 |
| 30497491 | 2018 | Chemotherapy-driven increases in the CDKN1A/PTN/PTPRZ1 axis promote chemoresistance by activating the NF-κB pathway in breast cancer cells. | 22 |
| 29651006 | 2018 | Cyclin-dependent kinase 5 mediates pleiotrophin-induced endothelial cell migration. | 12 |
Citation
Dessen P
PTPRZ1 (protein tyrosine phosphatase receptor type Z1)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41941/ptprz1
