RAB13 (RAB13, member RAS oncogene family)

2003-11-01  

Identity

HGNC
LOCATION
1q21.3
LOCUSID
ALIAS
GIG4
FUSION GENES

Other Information

Locus ID:

NCBI: 5872
MIM: 602672
HGNC: 9762
Ensembl: ENSG00000143545

Variants:

dbSNP: 5872
ClinVar: 5872
TCGA: ENSG00000143545
COSMIC: RAB13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143545ENST00000368575P51153
ENSG00000143545ENST00000614713A0A087WWB9

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Tight junctionKEGGko04530
Tight junctionKEGGhsa04530
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Translocation of GLUT4 to the plasma membraneREACTOMER-HSA-1445148
RAB GEFs exchange GTP for GDP on RABsREACTOMER-HSA-8876198
RAB geranylgeranylationREACTOMER-HSA-8873719

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
369017672023Construction of Two Independent RAB Family-Based Scoring Systems Based on Machine Learning Algorithms and Definition of RAB13 as a Novel Therapeutic Target for Hepatocellular Carcinoma.1
370463452023Single-cell transcriptomics in ovarian cancer identify a metastasis-associated cell cluster overexpressed RAB13.4
369017672023Construction of Two Independent RAB Family-Based Scoring Systems Based on Machine Learning Algorithms and Definition of RAB13 as a Novel Therapeutic Target for Hepatocellular Carcinoma.1
370463452023Single-cell transcriptomics in ovarian cancer identify a metastasis-associated cell cluster overexpressed RAB13.4
346326552021Identification of autophagic target RAB13 with small-molecule inhibitor in low-grade glioma via integrated multi-omics approaches coupled with virtual screening of traditional Chinese medicine databases.8
346326552021Identification of autophagic target RAB13 with small-molecule inhibitor in low-grade glioma via integrated multi-omics approaches coupled with virtual screening of traditional Chinese medicine databases.8
329461362020RNA localization and co-translational interactions control RAB13 GTPase function and cell migration.28
329461362020RNA localization and co-translational interactions control RAB13 GTPase function and cell migration.28
310765152019GGA2 and RAB13 promote activity-dependent β1-integrin recycling.21
314743342019RAB13 as a novel prognosis marker promotes proliferation and chemotherapeutic resistance in gastric cancer.9
310765152019GGA2 and RAB13 promote activity-dependent β1-integrin recycling.21
314743342019RAB13 as a novel prognosis marker promotes proliferation and chemotherapeutic resistance in gastric cancer.9
280873442017Up-regulation of the active form of small GTPase Rab13 promotes macroautophagy in vascular endothelial cells.9
280873442017Up-regulation of the active form of small GTPase Rab13 promotes macroautophagy in vascular endothelial cells.9
269691622016Rab13 Traffics on Vesicles Independent of Prenylation.8

Citation

Dessen P

RAB13 (RAB13, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/41958/rab13