Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57111
MIM: 612942
HGNC: 18238
Ensembl: ENSG00000132698
Variants:
dbSNP: 57111
ClinVar: 57111
TCGA: ENSG00000132698
COSMIC: RAB25
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000132698 | ENST00000361084 | P57735 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism of proteins | REACTOME | R-HSA-392499 |
| Post-translational protein modification | REACTOME | R-HSA-597592 |
| RAB geranylgeranylation | REACTOME | R-HSA-8873719 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38803515 | 2024 | Loss of RAB25 Cooperates with Oncogenes in the Transformation of Human Mammary Epithelial Cells (HMECs) to Give Rise to Claudin-Low Tumors. | 1 |
| 38803515 | 2024 | Loss of RAB25 Cooperates with Oncogenes in the Transformation of Human Mammary Epithelial Cells (HMECs) to Give Rise to Claudin-Low Tumors. | 1 |
| 37246119 | 2023 | Expression of Rab25 is down-regulated in the foreskin of children with hypospadias. | 0 |
| 37246119 | 2023 | Expression of Rab25 is down-regulated in the foreskin of children with hypospadias. | 0 |
| 33015770 | 2020 | Long non-coding RNA LINC00173 serves as sponge for miR-338-3p to promote prostate cancer progression via regulating Rab25. | 10 |
| 33015770 | 2020 | Long non-coding RNA LINC00173 serves as sponge for miR-338-3p to promote prostate cancer progression via regulating Rab25. | 10 |
| 30848009 | 2019 | Rab25 promotes erlotinib resistance by activating the β1 integrin/AKT/β-catenin pathway in NSCLC. | 15 |
| 31144312 | 2019 | Loss of Rab25 promotes the development of skin squamous cell carcinoma through the dysregulation of integrin trafficking. | 10 |
| 30848009 | 2019 | Rab25 promotes erlotinib resistance by activating the β1 integrin/AKT/β-catenin pathway in NSCLC. | 15 |
| 31144312 | 2019 | Loss of Rab25 promotes the development of skin squamous cell carcinoma through the dysregulation of integrin trafficking. | 10 |
| 29371698 | 2018 | Rab25 augments cancer cell invasiveness through a β1 integrin/EGFR/VEGF-A/Snail signaling axis and expression of fascin. | 31 |
| 29524309 | 2018 | MiR-577 suppresses epithelial-mesenchymal transition and metastasis of breast cancer by targeting Rab25. | 28 |
| 30445998 | 2018 | ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition. | 9 |
| 29371698 | 2018 | Rab25 augments cancer cell invasiveness through a β1 integrin/EGFR/VEGF-A/Snail signaling axis and expression of fascin. | 31 |
| 29524309 | 2018 | MiR-577 suppresses epithelial-mesenchymal transition and metastasis of breast cancer by targeting Rab25. | 28 |
Citation
Dessen P
RAB25 (RAB25, member RAS oncogene family)
Atlas Genet Cytogenet Oncol Haematol. 2004-02-01
Online version: http://atlasgeneticsoncology.org/gene/41970/rab25
