RAB43 (RAB43, member RAS oncogene family)

2004-02-01  

Identity

HGNC
LOCATION
3q21.3
LOCUSID
ALIAS
RAB11B,RAB41

Other Information

Locus ID:

NCBI: 339122
HGNC: 19983
Ensembl: ENSG00000172780

Variants:

dbSNP: 339122
ClinVar: 339122
TCGA: ENSG00000172780
COSMIC: RAB43

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172780ENST00000315150Q86YS6
ENSG00000172780ENST00000393304Q86YS6
ENSG00000172780ENST00000393305Q86YS6
ENSG00000172780ENST00000393307Q86YS6
ENSG00000172780ENST00000393308Q86YS6
ENSG00000172780ENST00000457077C9JFM7
ENSG00000172780ENST00000476465Q86YS6
ENSG00000172780ENST00000615093Q86YS6

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Retrograde transport at the Trans-Golgi-NetworkREACTOMER-HSA-6811440
RAB geranylgeranylationREACTOMER-HSA-8873719

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
355971252022miR-4742-5p promotes invasiveness of gastric cancer via targeting Rab43: An in vitro study.2
355971252022miR-4742-5p promotes invasiveness of gastric cancer via targeting Rab43: An in vitro study.2
321027522020Downregulation of TNFRSF19 and RAB43 by a novel miRNA, miR-HCC3, promotes proliferation and epithelial-mesenchymal transition in hepatocellular carcinoma cells.5
321027522020Downregulation of TNFRSF19 and RAB43 by a novel miRNA, miR-HCC3, promotes proliferation and epithelial-mesenchymal transition in hepatocellular carcinoma cells.5
312269642019A germline mutation in Rab43 gene identified from a cancer family predisposes to a hereditary liver-colon cancer syndrome.2
312269642019A germline mutation in Rab43 gene identified from a cancer family predisposes to a hereditary liver-colon cancer syndrome.2
280754782017High expression of RAB43 predicts poor prognosis and is associated with epithelial-mesenchymal transition in gliomas.11
290695902017The GTPase Rab43 Controls the Anterograde ER-Golgi Trafficking and Sorting of GPCRs.31
292339182017RhoB controls the Rab11-mediated recycling and surface reappearance of LFA-1 in migrating T lymphocytes.10
280754782017High expression of RAB43 predicts poor prognosis and is associated with epithelial-mesenchymal transition in gliomas.11
290695902017The GTPase Rab43 Controls the Anterograde ER-Golgi Trafficking and Sorting of GPCRs.31
292339182017RhoB controls the Rab11-mediated recycling and surface reappearance of LFA-1 in migrating T lymphocytes.10
235892912013The serum- and glucocorticoid-inducible kinases SGK1 and SGK3 regulate hERG channel expression via ubiquitin ligase Nedd4-2 and GTPase Rab11.25
236154422013Toxoplasma gondii salvages sphingolipids from the host Golgi through the rerouting of selected Rab vesicles to the parasitophorous vacuole.56
242483362013Structural basis of myosin V Rab GTPase-dependent cargo recognition.46

Citation

Dessen P

RAB43 (RAB43, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2004-02-01

Online version: http://atlasgeneticsoncology.org/gene/41997/rab43