Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51455
MIM: 606134
HGNC: 14060
Ensembl: ENSG00000135945
Variants:
dbSNP: 51455
ClinVar: 51455
TCGA: ENSG00000135945
COSMIC: REV1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA445601 | Osteosarcoma | Disease | ClinicalAnnotation | associated | PD | ||
| PA449014 | cisplatin | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38612916 | 2024 | The Catalytic Activity of Human REV1 on Undamaged and Damaged DNA. | 0 |
| 38612916 | 2024 | The Catalytic Activity of Human REV1 on Undamaged and Damaged DNA. | 0 |
| 35115490 | 2022 | REV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis. | 9 |
| 35115490 | 2022 | REV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis. | 9 |
| 33555350 | 2021 | Human Rev1 relies on insert-2 to promote selective binding and accurate replication of stabilized G-quadruplex motifs. | 9 |
| 34508659 | 2021 | REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps. | 65 |
| 34725419 | 2021 | Genetic and physical interactions between Polη and Rev1 in response to UV-induced DNA damage in mammalian cells. | 1 |
| 33555350 | 2021 | Human Rev1 relies on insert-2 to promote selective binding and accurate replication of stabilized G-quadruplex motifs. | 9 |
| 34508659 | 2021 | REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps. | 65 |
| 34725419 | 2021 | Genetic and physical interactions between Polη and Rev1 in response to UV-induced DNA damage in mammalian cells. | 1 |
| 32066793 | 2020 | Exome Sequencing in Individuals with Isolated Biliary Atresia. | 10 |
| 32066793 | 2020 | Exome Sequencing in Individuals with Isolated Biliary Atresia. | 10 |
| 30963698 | 2019 | Rev1 plays central roles in mammalian DNA-damage tolerance in response to UV irradiation. | 9 |
| 30963698 | 2019 | Rev1 plays central roles in mammalian DNA-damage tolerance in response to UV irradiation. | 9 |
| 29778604 | 2018 | Structural Basis for the Interaction of Mutasome Assembly Factor REV1 with Ubiquitin. | 6 |
Citation
Dessen P
REV1 (REV1 DNA directed polymerase)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/42085/rev1
