TRIM13 (tripartite motif containing 13)

2003-02-01  

Identity

HGNC
TRIM13
LOCATION
13q14.2
LOCUSID
10206
ALIAS
CAR,DLEU5,LEU5,RFP2,RNF77
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10206
MIM: 605661
HGNC: 9976
Ensembl: ENSG00000204977

Variants:

dbSNP: 10206
ClinVar: 10206
TCGA: ENSG00000204977
COSMIC: TRIM13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204977ENST00000356017O60858
ENSG00000204977ENST00000378182O60858
ENSG00000204977ENST00000378182A0A024RDU3
ENSG00000204977ENST00000378183X6R9U5
ENSG00000204977ENST00000420995O60858
ENSG00000204977ENST00000420995A0A024RDU3
ENSG00000204977ENST00000442421X6RH27
ENSG00000204977ENST00000457662O60858
ENSG00000204977ENST00000457662A0A024RDU3

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
N-glycan trimming in the ER and Calnexin/Calreticulin cycleREACTOMER-HSA-532668
Calnexin/calreticulin cycleREACTOMER-HSA-901042
ER Quality Control Compartment (ERQC)REACTOMER-HSA-901032

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
385376952024TRIM13 reduces cholesterol efflux and increases oxidized LDL uptake leading to foam cell formation and atherosclerosis.0
385376952024TRIM13 reduces cholesterol efflux and increases oxidized LDL uptake leading to foam cell formation and atherosclerosis.0
372450832023TRIM13 inhibits cell proliferation and induces autophagy in lung adenocarcinoma by regulating KEAP1/NRF2 pathway.2
372450832023TRIM13 inhibits cell proliferation and induces autophagy in lung adenocarcinoma by regulating KEAP1/NRF2 pathway.2
361809262022TRIM3 and TRIM16 as potential tumor suppressors in breast cancer patients.2
361809262022TRIM3 and TRIM16 as potential tumor suppressors in breast cancer patients.2
319018732020Altered DNA methylation of TRIM13 in diabetic nephropathy suppresses mesangial collagen synthesis by promoting ubiquitination of CHOP.13
319018732020Altered DNA methylation of TRIM13 in diabetic nephropathy suppresses mesangial collagen synthesis by promoting ubiquitination of CHOP.13
308373242019Bioinformatics analysis of prognostic value of TRIM13 gene in breast cancer.13
313570252019TRIM13 inhibited cell proliferation and induced cell apoptosis by regulating NF-κB pathway in non-small-cell lung carcinoma cells.22
308373242019Bioinformatics analysis of prognostic value of TRIM13 gene in breast cancer.13
313570252019TRIM13 inhibited cell proliferation and induced cell apoptosis by regulating NF-κB pathway in non-small-cell lung carcinoma cells.22
302248292018The E3 ubiquitin ligase Trim13 regulates Nur77 stability via casein kinase 2α.13
302248292018The E3 ubiquitin ligase Trim13 regulates Nur77 stability via casein kinase 2α.13
262882492015Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development.25

Citation

Dessen P

TRIM13 (tripartite motif containing 13)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42093/css/favicon/js/lib/bootstrap.min.js