Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 93587
MIM: 616013
HGNC: 28403
Ensembl: ENSG00000145331
Variants:
dbSNP: 93587
ClinVar: 93587
TCGA: ENSG00000145331
COSMIC: TRMT10A
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| tRNA processing | REACTOME | R-HSA-72306 |
| tRNA modification in the nucleus and cytosol | REACTOME | R-HSA-6782315 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32213595 | 2020 | Coordination of mRNA and tRNA methylations by TRMT10A. | 26 |
| 32392304 | 2020 | Functional characterization of the human tRNA methyltransferases TRMT10A and TRMT10B. | 24 |
| 32213595 | 2020 | Coordination of mRNA and tRNA methylations by TRMT10A. | 26 |
| 32392304 | 2020 | Functional characterization of the human tRNA methyltransferases TRMT10A and TRMT10B. | 24 |
| 31292261 | 2019 | Distinct substrate specificities of the human tRNA methyltransferases TRMT10A and TRMT10B. | 20 |
| 31292261 | 2019 | Distinct substrate specificities of the human tRNA methyltransferases TRMT10A and TRMT10B. | 20 |
| 30247717 | 2018 | Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes. | 66 |
| 30247717 | 2018 | Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes. | 66 |
| 26526202 | 2016 | tRNA methyltransferase homologue gene TRMT10A mutation in young adult-onset diabetes with intellectual disability, microcephaly and epilepsy. | 22 |
| 26526202 | 2016 | tRNA methyltransferase homologue gene TRMT10A mutation in young adult-onset diabetes with intellectual disability, microcephaly and epilepsy. | 22 |
| 26297882 | 2015 | Homozygous deletion of TRMT10A as part of a contiguous gene deletion in a syndrome of failure to thrive, delayed puberty, intellectual disability and diabetes mellitus. | 19 |
| 26297882 | 2015 | Homozygous deletion of TRMT10A as part of a contiguous gene deletion in a syndrome of failure to thrive, delayed puberty, intellectual disability and diabetes mellitus. | 19 |
| 25053765 | 2014 | TRMT10A dysfunction is associated with abnormalities in glucose homeostasis, short stature and microcephaly. | 53 |
| 25053765 | 2014 | TRMT10A dysfunction is associated with abnormalities in glucose homeostasis, short stature and microcephaly. | 53 |
| 24204302 | 2013 | tRNA methyltransferase homolog gene TRMT10A mutation in young onset diabetes and primary microcephaly in humans. | 59 |
Citation
Dessen P
TRMT10A (tRNA methyltransferase 10A)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42095/trmt10a
