RGR (retinal G protein coupled receptor)

2003-02-01 Affiliation

Identity

HGNC

RGR

LOCATION

10q23.1

LOCUSID

5995

ALIAS

RP44

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 5995
MIM: 600342
HGNC: 9990
Ensembl: ENSG00000148604

Variants:

dbSNP: 5995
ClinVar: 5995
TCGA: ENSG00000148604
COSMIC: RGR

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000148604	ENST00000358110	P47804
ENSG00000148604	ENST00000358110	A0A0S2Z494
ENSG00000148604	ENST00000359452	P47804
ENSG00000148604	ENST00000359452	A0A0S2Z498
ENSG00000148604	ENST00000478727	A0A494C1A1
ENSG00000148604	ENST00000483660	A0A494C1G9
ENSG00000148604	ENST00000483744	A0A494C1E7
ENSG00000148604	ENST00000497161	A0A494C0U5
ENSG00000148604	ENST00000650682	A0A494BZT6
ENSG00000148604	ENST00000650774	A0A494C170
ENSG00000148604	ENST00000651155	A0A494C1U1
ENSG00000148604	ENST00000651237	A0A494C063
ENSG00000148604	ENST00000652073	A0A494C063
ENSG00000148604	ENST00000652092	P47804
ENSG00000148604	ENST00000652122	A0A494C187
ENSG00000148604	ENST00000652310	A0A494C1A1

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Signal Transduction	REACTOME	R-HSA-162582
Signaling by GPCR	REACTOME	R-HSA-372790
GPCR ligand binding	REACTOME	R-HSA-500792
Class A/1 (Rhodopsin-like receptors)	REACTOME	R-HSA-373076
Opsins	REACTOME	R-HSA-419771
GPCR downstream signaling	REACTOME	R-HSA-388396
G alpha (i) signalling events	REACTOME	R-HSA-418594

References

Pubmed ID	Year	Title	Citations
38299232	2024	Expression Analysis of Retinal G Protein-coupled Receptor and its Correlation with Regulation of the Balance between Proliferation and Aberrant Differentiation in Cutaneous Squamous Cell Carcinoma.	0
38299232	2024	Expression Analysis of Retinal G Protein-coupled Receptor and its Correlation with Regulation of the Balance between Proliferation and Aberrant Differentiation in Cutaneous Squamous Cell Carcinoma.	0
37883094	2023	Proteopathy Linked to Exon-Skipping Isoform of RGR-Opsin Contributes to the Pathogenesis of Age-Related Macular Degeneration.	0
38053380	2023	A pan-cancer analysis of RGR opsin expression and its downregulation associated with poor prognosis in glioma.	0
37883094	2023	Proteopathy Linked to Exon-Skipping Isoform of RGR-Opsin Contributes to the Pathogenesis of Age-Related Macular Degeneration.	0
38053380	2023	A pan-cancer analysis of RGR opsin expression and its downregulation associated with poor prognosis in glioma.	0
34022179	2021	Human RGR Gene and Associated Features of Age-Related Macular Degeneration in Models of Retina-Choriocapillaris Atrophy.	2
34229535	2021	A rare case of RGR/CDHR1 haplotype identified in Bulgarian patient with cone-rod dystrophy.	1
34022179	2021	Human RGR Gene and Associated Features of Age-Related Macular Degeneration in Models of Retina-Choriocapillaris Atrophy.	2
34229535	2021	A rare case of RGR/CDHR1 haplotype identified in Bulgarian patient with cone-rod dystrophy.	1
30034210	2018	Coexpression of nonvisual opsin, retinal G protein-coupled receptor, and visual pigments in human and bovine cone photoreceptors.	5
30347075	2018	Clinical Features of a Retinopathy Associated With a Dominant Allele of the RGR Gene.	5
30034210	2018	Coexpression of nonvisual opsin, retinal G protein-coupled receptor, and visual pigments in human and bovine cone photoreceptors.	5
30347075	2018	Clinical Features of a Retinopathy Associated With a Dominant Allele of the RGR Gene.	5
27748892	2016	RGR variants in different forms of retinal diseases: The undetermined role of truncation mutations.	5

Citation

Dessen P

RGR (retinal G protein coupled receptor)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42098