RNF34 (ring finger protein 34)

2003-02-01  

Identity

HGNC
LOCATION
12q24.31
LOCUSID
ALIAS
CARP-1,CARP1,RFI,RIF,RIFF,hRFI
FUSION GENES

Other Information

Locus ID:

NCBI: 80196
MIM: 608299
HGNC: 17297
Ensembl: ENSG00000170633

Variants:

dbSNP: 80196
ClinVar: 80196
TCGA: ENSG00000170633
COSMIC: RNF34

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170633ENST00000361234Q969K3
ENSG00000170633ENST00000392464H7BYJ1
ENSG00000170633ENST00000392465Q969K3
ENSG00000170633ENST00000554606G3V504
ENSG00000170633ENST00000554868G3V5F1
ENSG00000170633ENST00000555076G3V566
ENSG00000170633ENST00000557402G3V4D1
ENSG00000170633ENST00000613529A0A087WTM5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
Regulation of TP53 ActivityREACTOMER-HSA-5633007
Regulation of TP53 Expression and DegradationREACTOMER-HSA-6806003
Regulation of TP53 DegradationREACTOMER-HSA-6804757

References

Pubmed IDYearTitleCitations
313046252019RNF34 functions in immunity and selective mitophagy by targeting MAVS for autophagic degradation.58
313046252019RNF34 functions in immunity and selective mitophagy by targeting MAVS for autophagic degradation.58
250122192014The E3 ligase RNF34 is a novel negative regulator of the NOD1 pathway.12
250122192014The E3 ligase RNF34 is a novel negative regulator of the NOD1 pathway.12
213087452011Destabilization of CARP mRNAs by aloe-emodin contributes to caspase-8-mediated p53-independent apoptosis of human carcinoma cells.9
213087452011Destabilization of CARP mRNAs by aloe-emodin contributes to caspase-8-mediated p53-independent apoptosis of human carcinoma cells.9
205642612010Uncoupling of bait-protein expression from the prey protein environment adds versatility for cell and tissue interaction proteomics and reveals a complex of CARP-1 and the PKA Cbeta1 subunit.3
205642612010Uncoupling of bait-protein expression from the prey protein environment adds versatility for cell and tissue interaction proteomics and reveals a complex of CARP-1 and the PKA Cbeta1 subunit.3
183821272008CARPs enhance p53 turnover by degrading 14-3-3sigma and stabilizing MDM2.21
183821272008CARPs enhance p53 turnover by degrading 14-3-3sigma and stabilizing MDM2.21
155956432004Effects of expression of hRFI on adenoma formation and tumor progression in colorectal adenoma-carcinoma sequence.4
155956432004Effects of expression of hRFI on adenoma formation and tumor progression in colorectal adenoma-carcinoma sequence.4
121183832002Isolation and characterization of a novel gene, hRFI, preferentially expressed in esophageal cancer.6
121183832002Isolation and characterization of a novel gene, hRFI, preferentially expressed in esophageal cancer.6

Citation

Dessen P

RNF34 (ring finger protein 34)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42136/rnf34