Identity
HGNC
LOCATION
18q11.1
LOCUSID
ALIAS
P160ROCK,ROCK-I
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6093
MIM: 601702
HGNC: 10251
Ensembl: ENSG00000067900
Variants:
dbSNP: 6093
ClinVar: 6093
TCGA: ENSG00000067900
COSMIC: ROCK1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000067900 | ENST00000399799 | Q13464 |
| ENSG00000067900 | ENST00000578051 | J3KRH6 |
| ENSG00000067900 | ENST00000635540 | A0A0U1RQV4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37801199 | 2024 | LAMB3 Promotes Myofibrogenesis and Cytoskeletal Reorganization in Endometrial Stromal Cells via the RhoA/ROCK1/MYL9 Pathway. | 0 |
| 38199985 | 2024 | ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. | 0 |
| 38254202 | 2024 | Paxillin participates in the sphingosylphosphorylcholine-induced abnormal contraction of vascular smooth muscle by regulating Rho-kinase activation. | 0 |
| 38309317 | 2024 | LINC00645 inhibits renal cell carcinoma progression by interacting with HNRNPA2B1 to regulate the ROCK1 mRNA stability. | 0 |
| 37801199 | 2024 | LAMB3 Promotes Myofibrogenesis and Cytoskeletal Reorganization in Endometrial Stromal Cells via the RhoA/ROCK1/MYL9 Pathway. | 0 |
| 38199985 | 2024 | ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. | 0 |
| 38254202 | 2024 | Paxillin participates in the sphingosylphosphorylcholine-induced abnormal contraction of vascular smooth muscle by regulating Rho-kinase activation. | 0 |
| 38309317 | 2024 | LINC00645 inhibits renal cell carcinoma progression by interacting with HNRNPA2B1 to regulate the ROCK1 mRNA stability. | 0 |
| 36513954 | 2023 | LINC00536 Promotes Breast Cancer Progression by Regulating ROCK1 via Sponging of miR-214-5p. | 1 |
| 36658407 | 2023 | Tumor-suppressing effects of miR-381-3p in pediatric acute myeloid leukemia via ROCK1 downregulation. | 0 |
| 37052185 | 2023 | lncRNA NEAT1 mediates LPS-induced pyroptosis of BEAS-2B cells via targeting miR-26a-5p/ROCK1 axis. | 0 |
| 37210870 | 2023 | Negative pressure induces dedifferentiation of hepatocytes via RhoA/ROCK pathway. | 0 |
| 37683138 | 2023 | Identification of ROCK1 as a novel biomarker for postmenopausal osteoporosis and pan-cancer analysis. | 0 |
| 36513954 | 2023 | LINC00536 Promotes Breast Cancer Progression by Regulating ROCK1 via Sponging of miR-214-5p. | 1 |
| 36658407 | 2023 | Tumor-suppressing effects of miR-381-3p in pediatric acute myeloid leukemia via ROCK1 downregulation. | 0 |
Citation
Dessen P
ROCK1 (Rho associated coiled-coil containing protein kinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42141/rock1
