RPL27A (ribosomal protein L27a)

2003-06-01  

Identity

HGNC
LOCATION
11p15.4
LOCUSID
ALIAS
L27A
FUSION GENES

Other Information

Locus ID:

NCBI: 6157
MIM: 603637
HGNC: 10329
Ensembl: ENSG00000166441

Variants:

dbSNP: 6157
ClinVar: 6157
TCGA: ENSG00000166441
COSMIC: RPL27A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166441ENST00000314138P46776
ENSG00000166441ENST00000524496E9PJD9
ENSG00000166441ENST00000525981H0YF34
ENSG00000166441ENST00000526562E9PJD9
ENSG00000166441ENST00000530022E9PJD9
ENSG00000166441ENST00000530913E9PJD9
ENSG00000166441ENST00000531978E9PLL6
ENSG00000166441ENST00000532359E9PLX7
ENSG00000166441ENST00000534599E9PKT2

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500

Pathways

PathwaySourceExternal ID
RibosomeKEGGko03010
RibosomeKEGGhsa03010
Ribosome, eukaryotesKEGGhsa_M00177
Ribosome, eukaryotesKEGGM00177
Metabolism of proteinsREACTOMER-HSA-392499
TranslationREACTOMER-HSA-72766
Eukaryotic Translation InitiationREACTOMER-HSA-72613
Cap-dependent Translation InitiationREACTOMER-HSA-72737
Formation of a pool of free 40S subunitsREACTOMER-HSA-72689
GTP hydrolysis and joining of the 60S ribosomal subunitREACTOMER-HSA-72706
L13a-mediated translational silencing of Ceruloplasmin expressionREACTOMER-HSA-156827
SRP-dependent cotranslational protein targeting to membraneREACTOMER-HSA-1799339
Eukaryotic Translation ElongationREACTOMER-HSA-156842
Peptide chain elongationREACTOMER-HSA-156902
Eukaryotic Translation TerminationREACTOMER-HSA-72764
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
Influenza InfectionREACTOMER-HSA-168254
Influenza Life CycleREACTOMER-HSA-168255
Influenza Viral RNA Transcription and ReplicationREACTOMER-HSA-168273
Viral mRNA TranslationREACTOMER-HSA-192823
Gene ExpressionREACTOMER-HSA-74160
Nonsense-Mediated Decay (NMD)REACTOMER-HSA-927802
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)REACTOMER-HSA-975957
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)REACTOMER-HSA-975956
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Selenoamino acid metabolismREACTOMER-HSA-2408522
Selenocysteine synthesisREACTOMER-HSA-2408557
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
374749472023High expression of RPL27A predicts poor prognosis in patients with hepatocellular carcinoma.1
374749472023High expression of RPL27A predicts poor prognosis in patients with hepatocellular carcinoma.1
350309752022tRF-19-W4PU732S promotes breast cancer cell malignant activity by targeting inhibition of RPL27A (ribosomal protein-L27A).12
350309752022tRF-19-W4PU732S promotes breast cancer cell malignant activity by targeting inhibition of RPL27A (ribosomal protein-L27A).12
273741042016RPL27A is a target of miR-595 and may contribute to the myelodysplastic phenotype through ribosomal dysgenesis.14
273741042016RPL27A is a target of miR-595 and may contribute to the myelodysplastic phenotype through ribosomal dysgenesis.14

Citation

Dessen P

RPL27A (ribosomal protein L27a)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42153/rpl27a