Identity
HGNC
LOCATION
11q13.2
LOCUSID
ALIAS
KLS,P70-beta,P70-beta-1,P70-beta-2,S6K-beta2,S6K2,S6KB,S6KI(2),S6Kbeta,SRK,STK14B,p70(S6K)-beta,p70S6Kb
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6199
MIM: 608939
HGNC: 10437
Ensembl: ENSG00000175634
Variants:
dbSNP: 6199
ClinVar: 6199
TCGA: ENSG00000175634
COSMIC: RPS6KB2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38281249 | 2024 | Ribosomal protein S6 kinase 2 (RPS6KB2) is a potential immunotherapeutic target for cancer that upregulates proinflammatory cytokines. | 0 |
| 38281249 | 2024 | Ribosomal protein S6 kinase 2 (RPS6KB2) is a potential immunotherapeutic target for cancer that upregulates proinflammatory cytokines. | 0 |
| 34705606 | 2021 | NSUN6, an RNA methyltransferase of 5-mC controls glioblastoma response to temozolomide (TMZ) via NELFB and RPS6KB2 interaction. | 15 |
| 34705606 | 2021 | NSUN6, an RNA methyltransferase of 5-mC controls glioblastoma response to temozolomide (TMZ) via NELFB and RPS6KB2 interaction. | 15 |
| 32054043 | 2020 | Distinct Roles of mTOR Targets S6K1 and S6K2 in Breast Cancer. | 29 |
| 32732916 | 2020 | Circ-GLI1 promotes metastasis in melanoma through interacting with p70S6K2 to activate Hedgehog/GLI1 and Wnt/β-catenin pathways and upregulate Cyr61. | 28 |
| 33003310 | 2020 | Activation of Mechanistic Target of Rapamycin (mTOR) in Human Endothelial Cells Infected with Pathogenic Spotted Fever Group Rickettsiae. | 6 |
| 32054043 | 2020 | Distinct Roles of mTOR Targets S6K1 and S6K2 in Breast Cancer. | 29 |
| 32732916 | 2020 | Circ-GLI1 promotes metastasis in melanoma through interacting with p70S6K2 to activate Hedgehog/GLI1 and Wnt/β-catenin pathways and upregulate Cyr61. | 28 |
| 33003310 | 2020 | Activation of Mechanistic Target of Rapamycin (mTOR) in Human Endothelial Cells Infected with Pathogenic Spotted Fever Group Rickettsiae. | 6 |
| 30320934 | 2019 | The polyproline-motif of S6K2: eIF5A translational dependence and importance for protein-protein interactions. | 2 |
| 30730779 | 2019 | S6K2 promises an important therapeutic potential for cancer. | 2 |
| 30320934 | 2019 | The polyproline-motif of S6K2: eIF5A translational dependence and importance for protein-protein interactions. | 2 |
| 30730779 | 2019 | S6K2 promises an important therapeutic potential for cancer. | 2 |
| 28301598 | 2017 | Regulation of anti-apoptotic Bcl-2 family protein Mcl-1 by S6 kinase 2. | 10 |
Citation
Dessen P
RPS6KB2 (ribosomal protein S6 kinase B2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42169/rps6kb2
