Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6256
MIM: 180245
HGNC: 10477
Ensembl: ENSG00000186350
Variants:
dbSNP: 6256
ClinVar: 6256
TCGA: ENSG00000186350
COSMIC: RXRA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000186350 | ENST00000481739 | P19793 |
| ENSG00000186350 | ENST00000481739 | F1D8Q5 |
| ENSG00000186350 | ENST00000649020 | A0A3B3IS44 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443340 | Anemia | Disease | ClinicalAnnotation | associated | PD | 24193570 | |
| PA445046 | Nasopharyngeal Neoplasms | Disease | ClinicalAnnotation | associated | PD | 24193570 | |
| PA445113 | Neutropenia | Disease | ClinicalAnnotation | associated | PD | 24193570 | |
| PA449383 | docetaxel | Chemical | ClinicalAnnotation | associated | PD | 24193570 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38205878 | 2024 | Linc-ROR inhibits NK cell-killing activity by promoting RXRA ubiquitination and reducing MICB expression in gastric cancer patients. | 0 |
| 38297280 | 2024 | ZNF148 inhibits HBV replication by downregulating RXRα transcription. | 1 |
| 38205878 | 2024 | Linc-ROR inhibits NK cell-killing activity by promoting RXRA ubiquitination and reducing MICB expression in gastric cancer patients. | 0 |
| 38297280 | 2024 | ZNF148 inhibits HBV replication by downregulating RXRα transcription. | 1 |
| 34971346 | 2023 | Computational refinement identifies functional destructive single nucleotide polymorphisms associated with human retinoid X receptor gene. | 0 |
| 37246895 | 2023 | lncRNA RMST suppresses the progression of colorectal cancer by competitively binding to miR-27a-3p/RXRα axis and inactivating Wnt signaling pathway. | 1 |
| 37499046 | 2023 | Stationary-to-migratory transition in glioblastoma stem-like cells driven by a fatty acid-binding protein 7-RXRα neurogenic pathway. | 4 |
| 37563580 | 2023 | SNP rs11185644 in RXRA gene and SNP rs2235544 in DIO1 gene predict dosage requirements in a cross-sectional sample of hypothyroid patients. | 0 |
| 34971346 | 2023 | Computational refinement identifies functional destructive single nucleotide polymorphisms associated with human retinoid X receptor gene. | 0 |
| 37246895 | 2023 | lncRNA RMST suppresses the progression of colorectal cancer by competitively binding to miR-27a-3p/RXRα axis and inactivating Wnt signaling pathway. | 1 |
| 37499046 | 2023 | Stationary-to-migratory transition in glioblastoma stem-like cells driven by a fatty acid-binding protein 7-RXRα neurogenic pathway. | 4 |
| 37563580 | 2023 | SNP rs11185644 in RXRA gene and SNP rs2235544 in DIO1 gene predict dosage requirements in a cross-sectional sample of hypothyroid patients. | 0 |
| 34870752 | 2022 | The role of resveratrol, Sirtuin1 and RXRα as prognostic markers in ovarian cancer. | 2 |
| 35406808 | 2022 | Cytoplasmic Colocalization of RXRα and PPARγ as an Independent Negative Prognosticator for Breast Cancer Patients. | 4 |
| 36484839 | 2022 | Integrated analysis of mRNA-seq and miRNA-seq reveals the potential roles of Egr1, Rxra and Max in kidney stone disease. | 1 |
Citation
Dessen P
RXRA (retinoid X receptor alpha)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42186/rxra
