RXRG (retinoid X receptor gamma)

2003-05-01  

Identity

HGNC
LOCATION
1q23.3
LOCUSID
ALIAS
NR2B3,RXRC
FUSION GENES

Other Information

Locus ID:

NCBI: 6258
MIM: 180247
HGNC: 10479
Ensembl: ENSG00000143171

Variants:

dbSNP: 6258
ClinVar: 6258
TCGA: ENSG00000143171
COSMIC: RXRG

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143171ENST00000359842P48443
ENSG00000143171ENST00000359842F1D8Q7
ENSG00000143171ENST00000619224A0A087WZ88

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
PPAR signaling pathwayKEGGko03320
Adipocytokine signaling pathwayKEGGko04920
Thyroid cancerKEGGko05216
Small cell lung cancerKEGGko05222
Non-small cell lung cancerKEGGko05223
PPAR signaling pathwayKEGGhsa03320
Adipocytokine signaling pathwayKEGGhsa04920
Pathways in cancerKEGGhsa05200
Thyroid cancerKEGGhsa05216
Small cell lung cancerKEGGhsa05222
Non-small cell lung cancerKEGGhsa05223
Transcriptional misregulation in cancerKEGGko05202
Transcriptional misregulation in cancerKEGGhsa05202
Thyroid hormone signaling pathwayKEGGhsa04919
Signal TransductionREACTOMER-HSA-162582
Signaling by Retinoic AcidREACTOMER-HSA-5362517
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Nuclear Receptor transcription pathwayREACTOMER-HSA-383280
Th17 cell differentiationKEGGko04659
Th17 cell differentiationKEGGhsa04659

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
346334452021Association between functional genetic variants in retinoid X receptor-α/γ and the risk of gestational diabetes mellitus in a southern Chinese population.3
346334452021Association between functional genetic variants in retinoid X receptor-α/γ and the risk of gestational diabetes mellitus in a southern Chinese population.3
318083862020Association between Single-nucleotide Polymorphisms of RXRG and Genetic Susceptibility to Type 2 Diabetes in South China.2
318083862020Association between Single-nucleotide Polymorphisms of RXRG and Genetic Susceptibility to Type 2 Diabetes in South China.2
313593852019Proteomics to Predict Loss of RXR-γ During Progression of Epithelial Ovarian Cancer.2
313593852019Proteomics to Predict Loss of RXR-γ During Progression of Epithelial Ovarian Cancer.2
272454362016Whole-exome identifies RXRG and TH germline variants in familial isolated prolactinoma.3
276369962016Genetic variants in vitamin D signaling pathways and risk of gestational diabetes mellitus.13
277211132016A vitamin D pathway gene-gene interaction affects low-density lipoprotein cholesterol levels.7
272454362016Whole-exome identifies RXRG and TH germline variants in familial isolated prolactinoma.3
276369962016Genetic variants in vitamin D signaling pathways and risk of gestational diabetes mellitus.13
277211132016A vitamin D pathway gene-gene interaction affects low-density lipoprotein cholesterol levels.7
261489732015Selective ligand activity at Nur/retinoid X receptor complexes revealed by dimer-specific bioluminescence resonance energy transfer-based sensors.10
263555502015Pregnane X Receptor Expression in Human Pancreatic Adenocarcinoma: Associations With Clinicopathologic Parameters, Tumor Proliferative Capacity, Patients' Survival, and Retinoid X Receptor Expression.8
261489732015Selective ligand activity at Nur/retinoid X receptor complexes revealed by dimer-specific bioluminescence resonance energy transfer-based sensors.10

Citation

Dessen P

RXRG (retinoid X receptor gamma)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42188/rxrg