SHISA5 (shisa family member 5)

2003-02-01  

Identity

HGNC
SHISA5
LOCATION
3p21.31
LOCUSID
51246
ALIAS
SCOTIN
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51246
MIM: 607290
HGNC: 30376
Ensembl: ENSG00000164054

Variants:

dbSNP: 51246
ClinVar: 51246
TCGA: ENSG00000164054
COSMIC: SHISA5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164054ENST00000296444Q8N114
ENSG00000164054ENST00000415268F8WCE2
ENSG00000164054ENST00000417841C9IZ46
ENSG00000164054ENST00000417962H7C2R0
ENSG00000164054ENST00000424965F8WFD9
ENSG00000164054ENST00000426002Q8N114
ENSG00000164054ENST00000441507F8WDS1
ENSG00000164054ENST00000442747Q8N114
ENSG00000164054ENST00000442747A0A024R2S8
ENSG00000164054ENST00000443308Q8N114
ENSG00000164054ENST00000444115Q8N114
ENSG00000164054ENST00000444115A0A024R2S8
ENSG00000164054ENST00000612611A0A087WZK8
ENSG00000164054ENST00000619810Q8N114
ENSG00000164054ENST00000619810A0A024R2S8

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
p53 signaling pathwayKEGGko04115
p53 signaling pathwayKEGGhsa04115

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
268682722016Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A.47
268682722016Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A.47
193675812010Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population.15
193675812010Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population.15
178898232007The calcium binding protein ALG-2 binds and stabilizes Scotin, a p53-inducible gene product localized at the endoplasmic reticulum membrane.9
178898232007The calcium binding protein ALG-2 binds and stabilizes Scotin, a p53-inducible gene product localized at the endoplasmic reticulum membrane.9
121359832002Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane.38
121359832002Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane.38

Citation

Dessen P

SHISA5 (shisa family member 5)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42217/cancer-prone-explorer/gene-fusions-explorer/favicon/apple-touch-icon.png