SERPINF1 (serpin family F member 1)

2003-08-01  

Identity

HGNC
SERPINF1
LOCATION
17p13.3
LOCUSID
5176
ALIAS
EPC-1,OI12,OI6,PEDF,PIG35
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5176
MIM: 172860
HGNC: 8824
Ensembl: ENSG00000132386

Variants:

dbSNP: 5176
ClinVar: 5176
TCGA: ENSG00000132386
COSMIC: SERPINF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132386ENST00000254722P36955
ENSG00000132386ENST00000254722A0A140VKF3
ENSG00000132386ENST00000570731I3L2R7
ENSG00000132386ENST00000571149I3L425
ENSG00000132386ENST00000571360I3L4Z0
ENSG00000132386ENST00000572048I3L107
ENSG00000132386ENST00000573763I3L4N7
ENSG00000132386ENST00000573770I3L1U4
ENSG00000132386ENST00000576406I3L4F9
ENSG00000132386ENST00000577053I3L3Z3

Expression (GTEx)

0
100
200
300
400
500
600
700
800
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Wnt signaling pathwayKEGGko04310
Wnt signaling pathwayKEGGhsa04310

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
383389742024Acute-Phase Plasma Pigment Epithelium-Derived Factor Predicting Outcomes after Aneurysmal Subarachnoid Hemorrhage in the Elderly.1
384880282024Pigment epithelium‑derived factor inhibits proliferation, invasion and angiogenesis, and induces ferroptosis of extravillous trophoblasts by targeting Wnt‑β‑catenin/VEGF signaling  in placenta accreta spectrum.0
383389742024Acute-Phase Plasma Pigment Epithelium-Derived Factor Predicting Outcomes after Aneurysmal Subarachnoid Hemorrhage in the Elderly.1
384880282024Pigment epithelium‑derived factor inhibits proliferation, invasion and angiogenesis, and induces ferroptosis of extravillous trophoblasts by targeting Wnt‑β‑catenin/VEGF signaling  in placenta accreta spectrum.0
363092042023Pigment epithelium-derived factor downregulation in oestrogen receptor positive breast cancer bone metastases is associated with menopause.3
369808582023SERPINF1 Mediates Tumor Progression and Stemness in Glioma.2
371048522023Roles of pigment epithelium-derived factor in cardiomyocytes: implications for use as a cardioprotective therapeutic.0
373085662023Genetic variants and altered expression of SERPINF1 confer disease susceptibility in patients with otosclerosis.0
374405642023Pigment Epithelium-Derived Factor, a Novel Adipokine, Contributes to Gestational Diabetes Mellitus.0
377138932023Sex differences in serum pigment epithelium-derived factor in healthy individuals.1
378397842023Characterization of three adults and an adolescent with Osteogenesis Imperfecta type VI and a novel founder SERPINF1 variant.0
380528512023Pigment epithelium-derived factor (PEDF) represses the glucose transporter 1 (GLUT1) mRNA expression and may be a potential therapeutic agent in psoriasis: a case-control and experimental study.0
363092042023Pigment epithelium-derived factor downregulation in oestrogen receptor positive breast cancer bone metastases is associated with menopause.3
369808582023SERPINF1 Mediates Tumor Progression and Stemness in Glioma.2
371048522023Roles of pigment epithelium-derived factor in cardiomyocytes: implications for use as a cardioprotective therapeutic.0

Citation

Dessen P

SERPINF1 (serpin family F member 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/42268