Identity
HGNC
LOCATION
3q27.3
LOCUSID
ALIAS
SIAT1,ST6GalI,ST6N
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6480
MIM: 109675
HGNC: 10860
Ensembl: ENSG00000073849
Variants:
dbSNP: 6480
ClinVar: 6480
TCGA: ENSG00000073849
COSMIC: ST6GAL1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164781042 | flucloxacillin | Chemical | Literature, MultilinkAnnotation | associated | 19483685 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37326830 | 2024 | CCCTC-binding factor: the specific transcription factor of β-galactoside α-2,6-sialyltransferase 1 that upregulates the sialylation of anti-citrullinated protein antibodies in rheumatoid arthritis. | 2 |
| 38490094 | 2024 | N-linked α2,6-sialylation of integrin β1 by the sialyltransferase ST6Gal1 promotes cell proliferation and stemness in gestational trophoblastic disease. | 0 |
| 37326830 | 2024 | CCCTC-binding factor: the specific transcription factor of β-galactoside α-2,6-sialyltransferase 1 that upregulates the sialylation of anti-citrullinated protein antibodies in rheumatoid arthritis. | 2 |
| 38490094 | 2024 | N-linked α2,6-sialylation of integrin β1 by the sialyltransferase ST6Gal1 promotes cell proliferation and stemness in gestational trophoblastic disease. | 0 |
| 36528750 | 2023 | ST6GAL1 inhibits metastasis of hepatocellular carcinoma via modulating sialylation of MCAM on cell surface. | 6 |
| 36646912 | 2023 | Role of ST6GAL1 and ST6GAL2 in subversion of cellular signaling during enteroaggregative Escherichia coli infection of human intestinal epithelial cell lines. | 2 |
| 37364046 | 2023 | Role of the ST6GAL1 sialyltransferase in regulating ovarian cancer cell metabolism. | 1 |
| 37550801 | 2023 | ST6GAL1-mediated aberrant sialylation promotes prostate cancer progression. | 6 |
| 37643018 | 2023 | ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression. | 3 |
| 37660914 | 2023 | Sialylation of EGFR by ST6GAL1 induces receptor activation and modulates trafficking dynamics. | 5 |
| 38003522 | 2023 | Role of ST6GAL1 in Thyroid Cancers: Insights from Tissue Analysis and Genomic Datasets. | 0 |
| 36528750 | 2023 | ST6GAL1 inhibits metastasis of hepatocellular carcinoma via modulating sialylation of MCAM on cell surface. | 6 |
| 36646912 | 2023 | Role of ST6GAL1 and ST6GAL2 in subversion of cellular signaling during enteroaggregative Escherichia coli infection of human intestinal epithelial cell lines. | 2 |
| 37364046 | 2023 | Role of the ST6GAL1 sialyltransferase in regulating ovarian cancer cell metabolism. | 1 |
| 37550801 | 2023 | ST6GAL1-mediated aberrant sialylation promotes prostate cancer progression. | 6 |
Citation
Dessen P
ST6GAL1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/42295/st6gal1
