Identity
HGNC
LOCATION
5p13.2
LOCUSID
ALIAS
FBL1,FBXL1,FLB1,p45
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6502
MIM: 601436
HGNC: 10901
Ensembl: ENSG00000145604
Variants:
dbSNP: 6502
ClinVar: 6502
TCGA: ENSG00000145604
COSMIC: SKP2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37850885 | 2024 | A critical role of the endothelial S-phase kinase-associated protein 2/phosphatase and tensin homologue axis in angiogenesis and psoriasis. | 0 |
| 37871911 | 2024 | SKP2 Knockout in Rb1/p53-Deficient Mouse Models of Osteosarcoma Induces Immune Infiltration and Drives a Transcriptional Program with a Favorable Prognosis. | 3 |
| 38184273 | 2024 | Skp2: A critical molecule for ubiquitination and its role in cancer. | 0 |
| 38355807 | 2024 | Targeted inhibition of SCF(SKP2) confers anti-tumor activities resulting in a survival benefit in osteosarcoma. | 1 |
| 38396292 | 2024 | O-GlcNAcylation of E3 ubiquitin ligase SKP2 promotes hepatocellular carcinoma proliferation. | 0 |
| 38561375 | 2024 | Targeting RCC1 to block the human soft-tissue sarcoma by disrupting nucleo-cytoplasmic trafficking of Skp2. | 0 |
| 37850885 | 2024 | A critical role of the endothelial S-phase kinase-associated protein 2/phosphatase and tensin homologue axis in angiogenesis and psoriasis. | 0 |
| 37871911 | 2024 | SKP2 Knockout in Rb1/p53-Deficient Mouse Models of Osteosarcoma Induces Immune Infiltration and Drives a Transcriptional Program with a Favorable Prognosis. | 3 |
| 38184273 | 2024 | Skp2: A critical molecule for ubiquitination and its role in cancer. | 0 |
| 38355807 | 2024 | Targeted inhibition of SCF(SKP2) confers anti-tumor activities resulting in a survival benefit in osteosarcoma. | 1 |
| 38396292 | 2024 | O-GlcNAcylation of E3 ubiquitin ligase SKP2 promotes hepatocellular carcinoma proliferation. | 0 |
| 38561375 | 2024 | Targeting RCC1 to block the human soft-tissue sarcoma by disrupting nucleo-cytoplasmic trafficking of Skp2. | 0 |
| 36694914 | 2023 | SKP2 Contributes to AKT Activation by Ubiquitination Degradation of PHLPP1, Impedes Autophagy, and Facilitates the Survival of Thyroid Carcinoma. | 5 |
| 36797828 | 2023 | LncRNA POU6F2-AS2 contributes to malignant phenotypes and paclitaxel resistance by promoting SKP2 expression in stomach adenocarcinoma. | 1 |
| 37257769 | 2023 | Promoter methylation and enhanced SKP2 are associated with the downregulation of CDKN1C in cervical squamous cell carcinoma. | 1 |
Citation
Dessen P
SKP2 (S-phase kinase associated protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42307/skp2
