SLAMF1 (signaling lymphocytic activation molecule family member 1)

2003-11-01  

Identity

HGNC
SLAMF1
LOCATION
1q23.3
LOCUSID
6504
ALIAS
CD150,CDw150,SLAM
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6504
MIM: 603492
HGNC: 10903
Ensembl: ENSG00000117090

Variants:

dbSNP: 6504
ClinVar: 6504
TCGA: ENSG00000117090
COSMIC: SLAMF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000117090ENST00000235739Q96QJ2
ENSG00000117090ENST00000302035Q13291
ENSG00000117090ENST00000538290Q13291

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MeaslesKEGGko05162
MeaslesKEGGhsa05162

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
thymus
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
358530102022SLAMF1 is expressed and secreted by hepatocytes and the liver in nonalcoholic fatty liver disease.3
361108462022Identification of SLAMF1 as an immune-related key gene associated with rheumatoid arthritis and verified in mice collagen-induced arthritis model.4
358530102022SLAMF1 is expressed and secreted by hepatocytes and the liver in nonalcoholic fatty liver disease.3
361108462022Identification of SLAMF1 as an immune-related key gene associated with rheumatoid arthritis and verified in mice collagen-induced arthritis model.4
325788732021In chronic lymphocytic leukaemia, SLAMF1 deregulation is associated with genomic complexity and independently predicts a worse outcome.6
329549472021Neutrophil autophagy during human active tuberculosis is modulated by SLAMF1.16
329917562021SLAMF1 signaling induces Mycobacterium tuberculosis uptake leading to endolysosomal maturation in human macrophages.1
339043152021CD150 and CD180 are negative regulators of IL-10 expression and secretion in chronic lymphocytic leukemia B cells.5
339874472021SLAM/SAP Decreased Follicular Regulatory T Cells in Patients with Graves' Disease.2
349675402021SLAMF1/CD150 expression and topology in prostate and breast cancer cell lines.2
325788732021In chronic lymphocytic leukaemia, SLAMF1 deregulation is associated with genomic complexity and independently predicts a worse outcome.6
329549472021Neutrophil autophagy during human active tuberculosis is modulated by SLAMF1.16
329917562021SLAMF1 signaling induces Mycobacterium tuberculosis uptake leading to endolysosomal maturation in human macrophages.1
339043152021CD150 and CD180 are negative regulators of IL-10 expression and secretion in chronic lymphocytic leukemia B cells.5
339874472021SLAM/SAP Decreased Follicular Regulatory T Cells in Patients with Graves' Disease.2

Citation

Dessen P

SLAMF1 (signaling lymphocytic activation molecule family member 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/42309/gene-explorer/cancer-prone-explorer/case-report-explorer/