SLC22A18 (solute carrier family 22 member 18)

2003-02-01  

Identity

HGNC
LOCATION
11p15.4
LOCUSID
ALIAS
BWR1A,BWSCR1A,HET,IMPT1,ITM,ORCTL2,SLC22A1L,TSSC5,p45-BWR1A

Other Information

Locus ID:

NCBI: 5002
MIM: 602631
HGNC: 10964
Ensembl: ENSG00000110628

Variants:

dbSNP: 5002
ClinVar: 5002
TCGA: ENSG00000110628
COSMIC: SLC22A18

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000110628ENST00000347936Q96BI1
ENSG00000110628ENST00000380574Q96BI1
ENSG00000110628ENST00000449793E9PRM7
ENSG00000110628ENST00000485423E9PMN7
ENSG00000110628ENST00000649076Q96BI1

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Organic cation/anion/zwitterion transportREACTOMER-HSA-549132
Organic cation transportREACTOMER-HSA-549127

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
383660232024The effect of genetic variants of SLC22A18 on proliferation, migration, and invasion of colon cancer cells.0
383660232024The effect of genetic variants of SLC22A18 on proliferation, migration, and invasion of colon cancer cells.0
306357412019Knockdown of Orphan Transporter SLC22A18 Impairs Lipid Metabolism and Increases Invasiveness of HepG2 Cells.7
306357412019Knockdown of Orphan Transporter SLC22A18 Impairs Lipid Metabolism and Increases Invasiveness of HepG2 Cells.7
301452112018Involvement of an Orphan Transporter, SLC22A18, in Cell Growth and Drug Resistance of Human Breast Cancer MCF7 Cells.5
301452112018Involvement of an Orphan Transporter, SLC22A18, in Cell Growth and Drug Resistance of Human Breast Cancer MCF7 Cells.5
274028792016Parent-of-origin tumourigenesis is mediated by an essential imprinted modifier in SDHD-linked paragangliomas: SLC22A18 and CDKN1C are candidate tumour modifiers.10
274028792016Parent-of-origin tumourigenesis is mediated by an essential imprinted modifier in SDHD-linked paragangliomas: SLC22A18 and CDKN1C are candidate tumour modifiers.10
254988862015microRNA-137 functions as a tumor suppressor in human non-small cell lung cancer by targeting SLC22A18.25
261965902015Characterization of SLC22A18 as a tumor suppressor and novel biomarker in colorectal cancer.15
254988862015microRNA-137 functions as a tumor suppressor in human non-small cell lung cancer by targeting SLC22A18.25
261965902015Characterization of SLC22A18 as a tumor suppressor and novel biomarker in colorectal cancer.15
244814892014In vitro and in vivo radiosensitization of human glioma U251 cells induced by upregulated expression of SLC22A18.6
244814892014In vitro and in vivo radiosensitization of human glioma U251 cells induced by upregulated expression of SLC22A18.6
235142452013Predictive value of the SLC22A18 protein expression in glioblastoma patients receiving temozolomide therapy.2

Citation

Dessen P

SLC22A18 (solute carrier family 22 member 18)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42316/slc22a18