Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64750
MIM: 605532
HGNC: 16809
Ensembl: ENSG00000108854
Variants:
dbSNP: 64750
ClinVar: 64750
TCGA: ENSG00000108854
COSMIC: SMURF2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000108854 | ENST00000262435 | Q9HAU4 |
| ENSG00000108854 | ENST00000578386 | J3QRY2 |
| ENSG00000108854 | ENST00000582081 | J3QLG1 |
| ENSG00000108854 | ENST00000585301 | J3QQM4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38810422 | 2024 | FOXO1 regulates RUNX2 ubiquitination through SMURF2 in calcific aortic valve disease. | 0 |
| 38810422 | 2024 | FOXO1 regulates RUNX2 ubiquitination through SMURF2 in calcific aortic valve disease. | 0 |
| 34545207 | 2023 | E3 ubiquitin ligase SMURF2 prevents colorectal cancer by reducing the stability of the YY1 protein and inhibiting the SENP1/c-myc axis. | 7 |
| 37497010 | 2023 | SMURF2 facilitates ubiquitin-mediated degradation of ID2 to attenuate lung cancer cell proliferation. | 0 |
| 37537194 | 2023 | Smurf1 and Smurf2 mediated polyubiquitination and degradation of RNF220 suppresses Shh-group medulloblastoma. | 0 |
| 37800598 | 2023 | Flavin containing monooxygenase 2 regulates renal tubular cell fibrosis and paracrine secretion via SMURF2 in AKI‑CKD transformation. | 1 |
| 37828084 | 2023 | Loss of SMURF2 expression enhances RACK1 stability and promotes ovarian cancer progression. | 3 |
| 37861000 | 2023 | Smurf2-Mediated Ubiquitination of FOXO4 Regulates Oxygen-glucose Deprivation/Reperfusion-induced Pyroptosis of Cortical Neurons. | 1 |
| 34545207 | 2023 | E3 ubiquitin ligase SMURF2 prevents colorectal cancer by reducing the stability of the YY1 protein and inhibiting the SENP1/c-myc axis. | 7 |
| 37497010 | 2023 | SMURF2 facilitates ubiquitin-mediated degradation of ID2 to attenuate lung cancer cell proliferation. | 0 |
| 37537194 | 2023 | Smurf1 and Smurf2 mediated polyubiquitination and degradation of RNF220 suppresses Shh-group medulloblastoma. | 0 |
| 37800598 | 2023 | Flavin containing monooxygenase 2 regulates renal tubular cell fibrosis and paracrine secretion via SMURF2 in AKI‑CKD transformation. | 1 |
| 37828084 | 2023 | Loss of SMURF2 expression enhances RACK1 stability and promotes ovarian cancer progression. | 3 |
| 37861000 | 2023 | Smurf2-Mediated Ubiquitination of FOXO4 Regulates Oxygen-glucose Deprivation/Reperfusion-induced Pyroptosis of Cortical Neurons. | 1 |
| 35017630 | 2022 | SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability. | 5 |
Citation
Dessen P
SMURF2 (SMAD specific E3 ubiquitin protein ligase 2)
Atlas Genet Cytogenet Oncol Haematol. 2004-02-01
Online version: http://atlasgeneticsoncology.org/gene/42342/smurf2
