Identity
HGNC
LOCATION
6q25.3
LOCUSID
ALIAS
GClnc1,IPO-B,IPOB,MNSOD,MVCD6,Mn-SOD
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6648
MIM: 147460
HGNC: 11180
Ensembl: ENSG00000285441
Variants:
dbSNP: 6648
ClinVar: 6648
TCGA: ENSG00000285441
COSMIC: SOD2
RNA/Proteins
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443560 | Breast Neoplasms | Disease | ClinicalAnnotation | associated | PD | 25495407 | |
| PA444065 | Epilepsy | Disease | ClinicalAnnotation | associated | PD | ||
| PA444460 | Heroin Dependence | Disease | ClinicalAnnotation | associated | PD | 29459008 | |
| PA446155 | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Disease | ClinicalAnnotation | associated | PD | 27019981 | |
| PA448492 | asparaginase | Chemical | ClinicalAnnotation | associated | PD | 27019981 | |
| PA449165 | cyclophosphamide | Chemical | ClinicalAnnotation | associated | PD | ||
| PA450428 | methotrexate | Chemical | ClinicalAnnotation, MultilinkAnnotation | associated | PD | 25330300 | |
| PA450761 | paclitaxel | Chemical | ClinicalAnnotation | associated | PD | 25495407 | |
| PA451846 | valproic acid | Chemical | ClinicalAnnotation | associated | PD | ||
| PA452619 | heroin | Chemical | ClinicalAnnotation | associated | PD | 29459008 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36229195 | 2024 | SOD2 confers anlotinib resistance via regulation of mitochondrial damage in OSCC. | 2 |
| 37921754 | 2024 | Superoxide dismutase 2 scavenges ROS to promote osteogenic differentiation of human periodontal ligament stem cells by regulating Smad3 in alveolar bone-defective rats. | 2 |
| 38039740 | 2024 | The impact of the association between Val16Ala-SOD2 SNP and SOD2 immunohistochemistry expression in the prognosis of patients with esophageal cancer. | 0 |
| 38154571 | 2024 | Overexpression of manganese superoxide dismutase mitigates ACL injury-induced muscle atrophy, weakness and oxidative damage. | 1 |
| 38310354 | 2024 | SOD2 promotes the immunosuppressive function of mesenchymal stem cells at the expense of adipocyte differentiation. | 0 |
| 38375721 | 2024 | Variants rs2758346, rs5746094, and rs2758331 of SOD2 gene: association study with breast cancer in a Mexican population and their analysis in silico. | 0 |
| 38404215 | 2024 | Methyltransferase METTL3-mediated maturation of miR-4654 facilitates high glucose-induced apoptosis and oxidative stress in lens epithelial cells via decreasing SOD2. | 1 |
| 38412803 | 2024 | SOD2 orchestrates redox homeostasis in intervertebral discs: A novel insight into oxidative stress-mediated degeneration and therapeutic potential. | 3 |
| 36229195 | 2024 | SOD2 confers anlotinib resistance via regulation of mitochondrial damage in OSCC. | 2 |
| 37921754 | 2024 | Superoxide dismutase 2 scavenges ROS to promote osteogenic differentiation of human periodontal ligament stem cells by regulating Smad3 in alveolar bone-defective rats. | 2 |
| 38039740 | 2024 | The impact of the association between Val16Ala-SOD2 SNP and SOD2 immunohistochemistry expression in the prognosis of patients with esophageal cancer. | 0 |
| 38154571 | 2024 | Overexpression of manganese superoxide dismutase mitigates ACL injury-induced muscle atrophy, weakness and oxidative damage. | 1 |
| 38310354 | 2024 | SOD2 promotes the immunosuppressive function of mesenchymal stem cells at the expense of adipocyte differentiation. | 0 |
| 38375721 | 2024 | Variants rs2758346, rs5746094, and rs2758331 of SOD2 gene: association study with breast cancer in a Mexican population and their analysis in silico. | 0 |
| 38404215 | 2024 | Methyltransferase METTL3-mediated maturation of miR-4654 facilitates high glucose-induced apoptosis and oxidative stress in lens epithelial cells via decreasing SOD2. | 1 |
Citation
Dessen P
SOD2 (superoxide dismutase 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/42353/sod2
