SPIB (Spi-B transcription factor)

2003-02-01  

Identity

HGNC
LOCATION
19q13.33
LOCUSID
ALIAS
SPI-B
FUSION GENES

Other Information

Locus ID:

NCBI: 6689
MIM: 606802
HGNC: 11242
Ensembl: ENSG00000269404

Variants:

dbSNP: 6689
ClinVar: 6689
TCGA: ENSG00000269404
COSMIC: SPIB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000269404ENST00000270632Q01892
ENSG00000269404ENST00000439922Q01892
ENSG00000269404ENST00000594685M0R2J9
ENSG00000269404ENST00000595883Q01892
ENSG00000269404ENST00000595883A0A024R4I5
ENSG00000269404ENST00000596074M0R037
ENSG00000269404ENST00000597855M0QXA8

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
386229802024IGSF10 inhibits the metastasis of lung adenocarcinoma via the Spi-B/Integrin-β1 signaling pathway.0
386229802024IGSF10 inhibits the metastasis of lung adenocarcinoma via the Spi-B/Integrin-β1 signaling pathway.0
364001812023Peroxiredoxin2 regulates trophoblast proliferation and migration through SPIB-HDAC2 pathway.1
374526342023SPIB Knockdown Inhibits the Immune Escape of Ovarian Cancer Cells by Reducing PD-L1 (CD274) Expression and Inactivating the JAK/STAT Pathway.0
364001812023Peroxiredoxin2 regulates trophoblast proliferation and migration through SPIB-HDAC2 pathway.1
374526342023SPIB Knockdown Inhibits the Immune Escape of Ovarian Cancer Cells by Reducing PD-L1 (CD274) Expression and Inactivating the JAK/STAT Pathway.0
357707292022SPI1-related protein inhibits cervical cancer cell progression and prevents macrophage cell migration.1
358314112022Integrated transcriptomic and regulatory network analyses uncovers the role of let-7b-5p, SPIB, and HLA-DPB1 in sepsis.3
359691722022Comprehensive pan-cancer analysis reveals the prognostic value and immunological role of SPIB.3
357707292022SPI1-related protein inhibits cervical cancer cell progression and prevents macrophage cell migration.1
358314112022Integrated transcriptomic and regulatory network analyses uncovers the role of let-7b-5p, SPIB, and HLA-DPB1 in sepsis.3
359691722022Comprehensive pan-cancer analysis reveals the prognostic value and immunological role of SPIB.3
345300562021SPIB acts as a tumor suppressor by activating the NFkB and JNK signaling pathways through MAP4K1 in colorectal cancer cells.9
345300562021SPIB acts as a tumor suppressor by activating the NFkB and JNK signaling pathways through MAP4K1 in colorectal cancer cells.9
321299362020SPIB promotes anoikis resistance via elevated autolysosomal process in lung cancer cells.12

Citation

Dessen P

SPIB (Spi-B transcription factor)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42374/cancer-prone-explorer/css/case-report-explorer/