Identity
HGNC
LOCATION
1q21.3
LOCUSID
ALIAS
CORNIFIN,GADD33,SPR-IB,SPRR1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6699
MIM: 182266
HGNC: 11260
Ensembl: ENSG00000169469
Variants:
dbSNP: 6699
ClinVar: 6699
TCGA: ENSG00000169469
COSMIC: SPRR1B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000169469 | ENST00000307098 | P22528 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Keratinization | REACTOME | R-HSA-6805567 |
| Formation of the cornified envelope | REACTOME | R-HSA-6809371 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33501784 | 2021 | Identification of small proline-rich protein 1B (SPRR1B) as a prognostically predictive biomarker for lung adenocarcinoma by integrative bioinformatic analysis. | 13 |
| 33620575 | 2021 | Identification of oral squamous cell carcinoma markers MUC2 and SPRR1B downstream of TANGO. | 0 |
| 34808501 | 2021 | DGUOK-AS1 promotes cervical squamous cell carcinoma progression by suppressing miR-499a-5p that targets SPRR1B in vitro. | 5 |
| 33501784 | 2021 | Identification of small proline-rich protein 1B (SPRR1B) as a prognostically predictive biomarker for lung adenocarcinoma by integrative bioinformatic analysis. | 13 |
| 33620575 | 2021 | Identification of oral squamous cell carcinoma markers MUC2 and SPRR1B downstream of TANGO. | 0 |
| 34808501 | 2021 | DGUOK-AS1 promotes cervical squamous cell carcinoma progression by suppressing miR-499a-5p that targets SPRR1B in vitro. | 5 |
| 27304082 | 2017 | Expression of Cornified Envelope Proteins in Skin and Its Relationship with Atopic Dermatitis Phenotype. | 18 |
| 28859701 | 2017 | RNA sequencing and pathway analysis identify tumor necrosis factor alpha driven small proline-rich protein dysregulation in chronic rhinosinusitis. | 9 |
| 27304082 | 2017 | Expression of Cornified Envelope Proteins in Skin and Its Relationship with Atopic Dermatitis Phenotype. | 18 |
| 28859701 | 2017 | RNA sequencing and pathway analysis identify tumor necrosis factor alpha driven small proline-rich protein dysregulation in chronic rhinosinusitis. | 9 |
| 23954638 | 2013 | Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal. | 19 |
| 23954638 | 2013 | Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal. | 19 |
| 18643845 | 2009 | Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families. | 17 |
| 19601998 | 2009 | Variation in genes of the epidermal differentiation complex in German atopic dermatitis patients. | 3 |
| 18643845 | 2009 | Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families. | 17 |
Citation
Dessen P
SPRR1B (small proline rich protein 1B)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/42380/sprr1b
