Identity
HGNC
LOCATION
11q12.1
LOCUSID
ALIAS
FACT,FACT80,T160
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6749
MIM: 604328
HGNC: 11327
Ensembl: ENSG00000149136
Variants:
dbSNP: 6749
ClinVar: 6749
TCGA: ENSG00000149136
COSMIC: SSRP1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38517892 | 2024 | Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes. | 0 |
| 38517892 | 2024 | Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes. | 0 |
| 37084412 | 2023 | Histone chaperone SSRP1 is required for apoptosis inhibition and mitochondrial function in HCC via transcriptional promotion of TRAP1. | 0 |
| 37084412 | 2023 | Histone chaperone SSRP1 is required for apoptosis inhibition and mitochondrial function in HCC via transcriptional promotion of TRAP1. | 0 |
| 35013515 | 2022 | Electron microscopy analysis of ATP-independent nucleosome unfolding by FACT. | 13 |
| 36577379 | 2022 | Human FACT subunits coordinate to catalyze both disassembly and reassembly of nucleosomes. | 5 |
| 35013515 | 2022 | Electron microscopy analysis of ATP-independent nucleosome unfolding by FACT. | 13 |
| 36577379 | 2022 | Human FACT subunits coordinate to catalyze both disassembly and reassembly of nucleosomes. | 5 |
| 33688504 | 2021 | SSRP1 Is a Prognostic Biomarker Correlated with CD8(+) T Cell Infiltration in Hepatocellular Carcinoma (HCC). | 5 |
| 33852836 | 2021 | Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG. | 19 |
| 34271103 | 2021 | Histone chaperone FACT complex inhibitor CBL0137 interferes with DNA damage repair and enhances sensitivity of medulloblastoma to chemotherapy and radiation. | 10 |
| 34756889 | 2021 | Structural insights into multifunctionality of human FACT complex subunit hSSRP1. | 2 |
| 33688504 | 2021 | SSRP1 Is a Prognostic Biomarker Correlated with CD8(+) T Cell Infiltration in Hepatocellular Carcinoma (HCC). | 5 |
| 33852836 | 2021 | Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG. | 19 |
| 34271103 | 2021 | Histone chaperone FACT complex inhibitor CBL0137 interferes with DNA damage repair and enhances sensitivity of medulloblastoma to chemotherapy and radiation. | 10 |
Citation
Dessen P
SSRP1 (structure specific recognition protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42400/ssrp1
