SSTR4 (somatostatin receptor 4)

2003-02-01  

Identity

HGNC
SSTR4
LOCATION
20p11.21
LOCUSID
6754
ALIAS
SS-4-R,SS4-R,SS4R

Other Information

Locus ID:

NCBI: 6754
MIM: 182454
HGNC: 11333
Ensembl: ENSG00000132671

Variants:

dbSNP: 6754
ClinVar: 6754
TCGA: ENSG00000132671
COSMIC: SSTR4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132671ENST00000255008P31391

Expression (GTEx)

0
1
2
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Neuroactive ligand-receptor interactionKEGGko04080
Neuroactive ligand-receptor interactionKEGGhsa04080
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
339166202021Human Somatostatin SST(4) Receptor Transgenic Mice: Construction and Brain Expression Pattern Characterization.10
339166202021Human Somatostatin SST(4) Receptor Transgenic Mice: Construction and Brain Expression Pattern Characterization.10
330967762020Characterization of Neurons Expressing the Novel Analgesic Drug Target Somatostatin Receptor 4 in Mouse and Human Brains.18
330967762020Characterization of Neurons Expressing the Novel Analgesic Drug Target Somatostatin Receptor 4 in Mouse and Human Brains.18
264744342016Prognostic Value of Somatostatin Receptor Subtypes in Pancreatic Neuroendocrine Tumors.12
264744342016Prognostic Value of Somatostatin Receptor Subtypes in Pancreatic Neuroendocrine Tumors.12
259624062015An immunohistochemical investigation of the expression of somatostatin receptor subtypes - should therapeutic trials be performed to determine the efficacy of somatostatin analogs in treating advanced thyroid malignances?4
259624062015An immunohistochemical investigation of the expression of somatostatin receptor subtypes - should therapeutic trials be performed to determine the efficacy of somatostatin analogs in treating advanced thyroid malignances?4
246029812014Methylation analysis of SST and SSTR4 promoters in the neocortex of Alzheimer's disease patients.7
247437072014Regulation of somatostatin receptor 4-mediated cytostatic effects by CD26 in malignant pleural mesothelioma.10
246029812014Methylation analysis of SST and SSTR4 promoters in the neocortex of Alzheimer's disease patients.7
247437072014Regulation of somatostatin receptor 4-mediated cytostatic effects by CD26 in malignant pleural mesothelioma.10
239919552013Somatostatin receptors 3, 4 and 5 play important roles in gallbladder cancer.5
239919552013Somatostatin receptors 3, 4 and 5 play important roles in gallbladder cancer.5
201823882010Somatostatin receptor subtypes in human type 2 diabetic islets.4

Citation

Dessen P

SSTR4 (somatostatin receptor 4)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42404