Identity
HGNC
LOCATION
22q13.2
LOCUSID
ALIAS
AAG2,FAM10A1,FAM10A4,HIP,HOP,HSPABP,HSPABP1,P48,PRO0786,SNC6
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6767
MIM: 606796
HGNC: 11343
Ensembl: ENSG00000100380
Variants:
dbSNP: 6767
ClinVar: 6767
TCGA: ENSG00000100380
COSMIC: ST13
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cellular responses to stress | REACTOME | R-HSA-2262752 |
| Cellular response to heat stress | REACTOME | R-HSA-3371556 |
| Regulation of HSF1-mediated heat shock response | REACTOME | R-HSA-3371453 |
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10832 | corticosteroids | Chemical | ClinicalAnnotation | associated | PD | 25616159 | |
| PA443450 | Asthma | Disease | ClinicalAnnotation | associated | PD | 25616159 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38492099 | 2024 | Polymorphism in Genes Encoding Adaptor Proteins ST13 and STIP1 and the Risk of Ischemic Stroke: a Pilot Study. | 0 |
| 38492099 | 2024 | Polymorphism in Genes Encoding Adaptor Proteins ST13 and STIP1 and the Risk of Ischemic Stroke: a Pilot Study. | 0 |
| 32791689 | 2020 | An autophagy-related model of 4 key genes for predicting prognosis of patients with laryngeal cancer. | 3 |
| 32791689 | 2020 | An autophagy-related model of 4 key genes for predicting prognosis of patients with laryngeal cancer. | 3 |
| 25616159 | 2015 | ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults. | 15 |
| 25616159 | 2015 | ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults. | 15 |
| 23125081 | 2012 | ST13, a proliferation regulator, inhibits growth and migration of colorectal cancer cell lines. | 7 |
| 23125081 | 2012 | ST13, a proliferation regulator, inhibits growth and migration of colorectal cancer cell lines. | 7 |
| 21240662 | 2011 | Single-point mutation in a conserved TPR domain of Hip disrupts enhancement of glucocorticoid receptor signaling. | 0 |
| 21728385 | 2011 | G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4. | 23 |
| 21767636 | 2011 | Akt phosphorylation at Thr308 and Ser473 is required for CHIP-mediated ubiquitination of the kinase. | 21 |
| 21240662 | 2011 | Single-point mutation in a conserved TPR domain of Hip disrupts enhancement of glucocorticoid receptor signaling. | 0 |
| 21728385 | 2011 | G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4. | 23 |
| 21767636 | 2011 | Akt phosphorylation at Thr308 and Ser473 is required for CHIP-mediated ubiquitination of the kinase. | 21 |
| 20193743 | 2010 | Expression analysis of suppression of tumorigenicity 13 gene in patients with Parkinson's disease. | 4 |
Citation
Dessen P
ST13 (ST13 Hsp70 interacting protein)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42416/st13
