SULT1E1 (sulfotransferase family 1E member 1)

2003-08-01  

Identity

HGNC
LOCATION
4q13.3
LOCUSID
ALIAS
EST,EST-1,ST1E1,STE

Other Information

Locus ID:

NCBI: 6783
MIM: 600043
HGNC: 11377
Ensembl: ENSG00000109193

Variants:

dbSNP: 6783
ClinVar: 6783
TCGA: ENSG00000109193
COSMIC: SULT1E1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000109193ENST00000226444P49888
ENSG00000109193ENST00000226444Q53X91

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Steroid hormone biosynthesisKEGGko00140
Steroid hormone biosynthesisKEGGhsa00140
MetabolismREACTOMER-HSA-1430728
Biological oxidationsREACTOMER-HSA-211859
Phase II conjugationREACTOMER-HSA-156580
Cytosolic sulfonation of small moleculesREACTOMER-HSA-156584

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA448015acetaminophenChemicalLiterature, MultilinkAnnotation, Pathwayassociated23462933, 26049587

References

Pubmed IDYearTitleCitations
377246762023Estrogen Sulfotransferase SULT1E1 Expression Levels and Regulated Factors in Malignant Tumours.0
377246762023Estrogen Sulfotransferase SULT1E1 Expression Levels and Regulated Factors in Malignant Tumours.0
350599532022Estrogen Sulfotransferase is Highly Expressed in Vascular Endothelial Cells Overlying Atherosclerotic Plaques.1
350599532022Estrogen Sulfotransferase is Highly Expressed in Vascular Endothelial Cells Overlying Atherosclerotic Plaques.1
330642932021Impact of Human SULT1E1 Polymorphisms on the Sulfation of 17β-Estradiol, 4-Hydroxytamoxifen, and Diethylstilbestrol by SULT1E1 Allozymes.2
336657702021Interaction of Native- and Oxidized-Low-Density Lipoprotein with Human Estrogen Sulfotransferase.1
330642932021Impact of Human SULT1E1 Polymorphisms on the Sulfation of 17β-Estradiol, 4-Hydroxytamoxifen, and Diethylstilbestrol by SULT1E1 Allozymes.2
336657702021Interaction of Native- and Oxidized-Low-Density Lipoprotein with Human Estrogen Sulfotransferase.1
294363902018Identification of Galeterone and Abiraterone as Inhibitors of Dehydroepiandrosterone Sulfonation Catalyzed by Human Hepatic Cytosol, SULT2A1, SULT2B1b, and SULT1E1.4
299299822018Cholestasis-induced bile acid elevates estrogen level via farnesoid X receptor-mediated suppression of the estrogen sulfotransferase SULT1E1.18
302177852018The sulfatase pathway as estrogen supply in endometrial cancer.5
294363902018Identification of Galeterone and Abiraterone as Inhibitors of Dehydroepiandrosterone Sulfonation Catalyzed by Human Hepatic Cytosol, SULT2A1, SULT2B1b, and SULT1E1.4
299299822018Cholestasis-induced bile acid elevates estrogen level via farnesoid X receptor-mediated suppression of the estrogen sulfotransferase SULT1E1.18
302177852018The sulfatase pathway as estrogen supply in endometrial cancer.5
278540742017Resveratrol and its methoxy derivatives modulate the expression of estrogen metabolism enzymes in breast epithelial cells by AhR down-regulation.6

Citation

Dessen P

SULT1E1 (sulfotransferase family 1E member 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/42450/sult1e1