Identity
HGNC
LOCATION
1p32.1
LOCUSID
ALIAS
EGP-1,EGP1,GA733-1,GA7331,GP50,M1S1,TROP2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4070
MIM: 137290
HGNC: 11530
Ensembl: ENSG00000184292
Variants:
dbSNP: 4070
ClinVar: 4070
TCGA: ENSG00000184292
COSMIC: TACSTD2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000184292 | ENST00000371225 | P09758 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38048058 | 2024 | TROP2 Is Associated with Primary Resistance to Immune Checkpoint Inhibition in Patients with Advanced Non-Small Cell Lung Cancer. | 0 |
| 38073379 | 2024 | Diagnostic and prognostic utility of TROP-2, SLP-2, and CXCL12 expression in papillary thyroid carcinoma. | 0 |
| 38196202 | 2024 | Associations of TACSTD2/TROP2 and NECTIN-4/NECTIN-4 with molecular subtypes, PD-L1 expression, and FGFR3 mutational status in two advanced urothelial bladder cancer cohorts. | 2 |
| 38302503 | 2024 | DNA demethylation and tri-methylation of H3K4 at the TACSTD2 promoter are complementary players for TROP2 regulation in colorectal cancer cells. | 0 |
| 38685507 | 2024 | TROP2 promotes PINK1-mediated mitophagy and apoptosis to accelerate the progression of senile chronic obstructive pulmonary disease by up-regulating DRP1 expression. | 0 |
| 38048058 | 2024 | TROP2 Is Associated with Primary Resistance to Immune Checkpoint Inhibition in Patients with Advanced Non-Small Cell Lung Cancer. | 0 |
| 38073379 | 2024 | Diagnostic and prognostic utility of TROP-2, SLP-2, and CXCL12 expression in papillary thyroid carcinoma. | 0 |
| 38196202 | 2024 | Associations of TACSTD2/TROP2 and NECTIN-4/NECTIN-4 with molecular subtypes, PD-L1 expression, and FGFR3 mutational status in two advanced urothelial bladder cancer cohorts. | 2 |
| 38302503 | 2024 | DNA demethylation and tri-methylation of H3K4 at the TACSTD2 promoter are complementary players for TROP2 regulation in colorectal cancer cells. | 0 |
| 38685507 | 2024 | TROP2 promotes PINK1-mediated mitophagy and apoptosis to accelerate the progression of senile chronic obstructive pulmonary disease by up-regulating DRP1 expression. | 0 |
| 36759721 | 2023 | Trop-2 and Nectin-4 immunohistochemical expression in metastatic colorectal cancer: searching for the right population for drugs' development. | 4 |
| 37067548 | 2023 | TROP-2 is widely expressed in vulvar squamous cell carcinoma and represents a potential new therapeutic target. | 0 |
| 37121444 | 2023 | Targeting Trop-2 in cancer: Recent research progress and clinical application. | 6 |
| 37268280 | 2023 | TROP2 translation mediated by dual m(6)A/m(7)G RNA modifications promotes bladder cancer development. | 2 |
| 37380081 | 2023 | Trophoblast cell surface antigen-2 phosphorylation triggered by binding of galectin-3 drives metastasis through down-regulation of E-cadherin. | 2 |
Citation
Dessen P
TACSTD2 (tumor associated calcium signal transducer 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42460/tacstd2
