Identity
HGNC
LOCATION
2q24.2
LOCUSID
ALIAS
I-TRAF,ITRAF,TRAF2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10010
MIM: 603893
HGNC: 11562
Ensembl: ENSG00000136560
Variants:
dbSNP: 10010
ClinVar: 10010
TCGA: ENSG00000136560
COSMIC: TANK
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37215097 | 2023 | TANK shapes an immunosuppressive microenvironment and predicts prognosis and therapeutic response in glioma. | 0 |
| 37215097 | 2023 | TANK shapes an immunosuppressive microenvironment and predicts prognosis and therapeutic response in glioma. | 0 |
| 31486084 | 2020 | CARD14/CARMA2sh and TANK differentially regulate poly(I:C)-induced inflammatory reaction in keratinocytes. | 3 |
| 33316896 | 2020 | UBAC1/KPC2 Regulates TLR3 Signaling in Human Keratinocytes through Functional Interaction with the CARD14/CARMA2sh-TANK Complex. | 6 |
| 31486084 | 2020 | CARD14/CARMA2sh and TANK differentially regulate poly(I:C)-induced inflammatory reaction in keratinocytes. | 3 |
| 33316896 | 2020 | UBAC1/KPC2 Regulates TLR3 Signaling in Human Keratinocytes through Functional Interaction with the CARD14/CARMA2sh-TANK Complex. | 6 |
| 30721969 | 2019 | The Cortical Neuroimmune Regulator TANK Affects Emotional Processing and Enhances Alcohol Drinking: A Translational Study. | 5 |
| 30721969 | 2019 | The Cortical Neuroimmune Regulator TANK Affects Emotional Processing and Enhances Alcohol Drinking: A Translational Study. | 5 |
| 28155233 | 2017 | Molecular basis for TANK recognition by TRAF1 revealed by the crystal structure of TRAF1/TANK complex. | 9 |
| 28487378 | 2017 | Encephalomyocarditis virus 3C protease attenuates type I interferon production through disrupting the TANK-TBK1-IKKε-IRF3 complex. | 22 |
| 28566380 | 2017 | Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage. | 72 |
| 28155233 | 2017 | Molecular basis for TANK recognition by TRAF1 revealed by the crystal structure of TRAF1/TANK complex. | 9 |
| 28487378 | 2017 | Encephalomyocarditis virus 3C protease attenuates type I interferon production through disrupting the TANK-TBK1-IKKε-IRF3 complex. | 22 |
| 28566380 | 2017 | Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage. | 72 |
| 25861989 | 2015 | TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase. | 53 |
Citation
Dessen P
TANK (TRAF family member associated NFKB activator)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/42468/tank
