TDGF1 (teratocarcinoma-derived growth factor 1)

2003-02-01  

Identity

HGNC
LOCATION
3p21.31
LOCUSID
ALIAS
CR,CR-1,CRGF,CRIPTO
FUSION GENES

Other Information

Locus ID:

NCBI: 6997
MIM: 187395
HGNC: 11701
Ensembl: ENSG00000241186

Variants:

dbSNP: 6997
ClinVar: 6997
TCGA: ENSG00000241186
COSMIC: TDGF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000241186ENST00000296145P13385
ENSG00000241186ENST00000542931F5H1T8

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
Signaling by NODALREACTOMER-HSA-1181150
Regulation of signaling by NODALREACTOMER-HSA-1433617
Transcriptional regulation of pluripotent stem cellsREACTOMER-HSA-452723
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferationREACTOMER-HSA-2892247

References

Pubmed IDYearTitleCitations
354341292022CRIPTO-1 Is Immunolocalized in the Syncytiotrophoblast of Ampullary Pregnancies.1
354341292022CRIPTO-1 Is Immunolocalized in the Syncytiotrophoblast of Ampullary Pregnancies.1
339666942021[Expression and Prognostic Value of Cripto-1 in Pancreatic Cancer].1
343575952021Cripto favors chondrocyte hypertrophy via TGF-β SMAD1/5 signaling during development of osteoarthritis.6
345021882021Cripto-1 as a Key Factor in Tumor Progression, Epithelial to Mesenchymal Transition and Cancer Stem Cells.4
345173442021Liver-specific over-expression of Cripto-1 in transgenic mice promotes hepatocyte proliferation and deregulated expression of hepatocarcinogenesis-related genes and signaling pathways.2
345694982021miR-3929 Inhibits Proliferation and Promotes Apoptosis by Downregulating Cripto-1 Expression in Cervical Cancer Cells.1
349438322021Oncofetal Protein CRIPTO Is Involved in Wound Healing and Fibrogenesis in the Regenerating Liver and Is Associated with the Initial Stages of Cardiac Fibrosis.3
339666942021[Expression and Prognostic Value of Cripto-1 in Pancreatic Cancer].1
343575952021Cripto favors chondrocyte hypertrophy via TGF-β SMAD1/5 signaling during development of osteoarthritis.6
345021882021Cripto-1 as a Key Factor in Tumor Progression, Epithelial to Mesenchymal Transition and Cancer Stem Cells.4
345173442021Liver-specific over-expression of Cripto-1 in transgenic mice promotes hepatocyte proliferation and deregulated expression of hepatocarcinogenesis-related genes and signaling pathways.2
345694982021miR-3929 Inhibits Proliferation and Promotes Apoptosis by Downregulating Cripto-1 Expression in Cervical Cancer Cells.1
349438322021Oncofetal Protein CRIPTO Is Involved in Wound Healing and Fibrogenesis in the Regenerating Liver and Is Associated with the Initial Stages of Cardiac Fibrosis.3
316920302020KRAS mutation and abnormal expression of Cripto-1 as two potential candidate biomarkers for detection of colorectal cancer development.1

Citation

Dessen P

TDGF1 (teratocarcinoma-derived growth factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42507/tdgf1