TFPI2 (tissue factor pathway inhibitor 2)

2003-02-01  

Identity

HGNC
TFPI2
LOCATION
7q21.3
LOCUSID
7980
ALIAS
PP5,REF1,TFPI-2

Other Information

Locus ID:

NCBI: 7980
MIM: 600033
HGNC: 11761
Ensembl: ENSG00000105825

Variants:

dbSNP: 7980
ClinVar: 7980
TCGA: ENSG00000105825
COSMIC: TFPI2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105825ENST00000222543P48307
ENSG00000105825ENST00000451238H7C4A3
ENSG00000105825ENST00000647793A0A3B3IRW1
ENSG00000105825ENST00000649913A0A3B3ISY1
ENSG00000105825ENST00000650573A0A3B3IS67

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
367870852023Integrative analyses of RNA-seq and ChIP-seq Reveal MITF as a Target Gene of TFPI-2 in MDA231 Cells.0
371864952023The role of tissue factor pathway inhibitor 2 in the coagulation and fibrinolysis system.2
375499322023Tissue factor pathway inhibitor 2: Current understanding, challenges, and future perspectives.0
367870852023Integrative analyses of RNA-seq and ChIP-seq Reveal MITF as a Target Gene of TFPI-2 in MDA231 Cells.0
371864952023The role of tissue factor pathway inhibitor 2 in the coagulation and fibrinolysis system.2
375499322023Tissue factor pathway inhibitor 2: Current understanding, challenges, and future perspectives.0
350395722022MEG8 regulates Tissue Factor Pathway Inhibitor 2 (TFPI2) expression in the endothelium.7
352271952022The methylation of SDC2 and TFPI2 defined three methylator phenotypes of colorectal cancer.3
354041842022m(6)A RNA demethylase FTO promotes the growth, migration and invasion of pancreatic cancer cells through inhibiting TFPI-2.10
355013902022MBD3 promotes hepatocellular carcinoma progression and metastasis through negative regulation of tumour suppressor TFPI2.7
356135432022Tissue Factor Pathway Inhibitor 2: A Novel Biomarker for Predicting Asymptomatic Venous Thromboembolism in Patients with Epithelial Ovarian Cancer.5
359400822022Exosomal miR-195 in hUC-MSCs alleviates hypoxia-induced damage of trophoblast cells through tissue factor pathway inhibitor 2.2
364467912022HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation.13
350395722022MEG8 regulates Tissue Factor Pathway Inhibitor 2 (TFPI2) expression in the endothelium.7
352271952022The methylation of SDC2 and TFPI2 defined three methylator phenotypes of colorectal cancer.3

Citation

Dessen P

TFPI2 (tissue factor pathway inhibitor 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42532/tfpi2-(tissue-factor-pathway-inhibitor-2)