THBS3 (thrombospondin 3)

2003-08-01  

Identity

HGNC
THBS3
LOCATION
1q22
LOCUSID
7059
ALIAS
TSP3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7059
MIM: 188062
HGNC: 11787
Ensembl: ENSG00000169231

Variants:

dbSNP: 7059
ClinVar: 7059
TCGA: ENSG00000169231
COSMIC: THBS3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169231ENST00000368378P49746
ENSG00000169231ENST00000428962B4DQH6
ENSG00000169231ENST00000457183P49746
ENSG00000169231ENST00000541576F5H4Z8
ENSG00000169231ENST00000541990Q2HIZ1

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Focal adhesionKEGGko04510
ECM-receptor interactionKEGGko04512
Focal adhesionKEGGhsa04510
ECM-receptor interactionKEGGhsa04512
MalariaKEGGko05144
MalariaKEGGhsa05144
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151
Signal TransductionREACTOMER-HSA-162582
Signaling by PDGFREACTOMER-HSA-186797

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
375246132023Hyperuricemia and coronary heart disease: The mediating role of blood pressure and thrombospondin 3.0
375246132023Hyperuricemia and coronary heart disease: The mediating role of blood pressure and thrombospondin 3.0
339108542021Pathological Significance and Prognostic Roles of Thrombospondin-3, 4 and 5 in Bladder Cancer.3
339612902021Serum levels of the IgA isotype switch factor TGF-β1 are elevated in patients with COVID-19.13
346693622021mRNA Expression of thrombospondin 1, 2 and 3 from proximal to distal in human abdominal aortic aneurysm - preliminary report.2
339108542021Pathological Significance and Prognostic Roles of Thrombospondin-3, 4 and 5 in Bladder Cancer.3
339612902021Serum levels of the IgA isotype switch factor TGF-β1 are elevated in patients with COVID-19.13
346693622021mRNA Expression of thrombospondin 1, 2 and 3 from proximal to distal in human abdominal aortic aneurysm - preliminary report.2
170228222006Effects of THBS3, SPARC and SPP1 expression on biological behavior and survival in patients with osteosarcoma.49
170228222006Effects of THBS3, SPARC and SPP1 expression on biological behavior and survival in patients with osteosarcoma.49
119435892002Corneal stromal cells (keratocytes) express thrombospondins 2 and 3 in wound repair phenotype.7
119435892002Corneal stromal cells (keratocytes) express thrombospondins 2 and 3 in wound repair phenotype.7

Citation

Dessen P

THBS3 (thrombospondin 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/42550/gene-fusions/css/css/template-card.css