Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 100287932
MIM: 605034
HGNC: 17312
Ensembl: ENSG00000265354
Variants:
dbSNP: 100287932
ClinVar: 100287932
TCGA: ENSG00000265354
COSMIC: TIMM23
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000265354 | ENST00000580018 | O14925 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism of proteins | REACTOME | R-HSA-392499 |
| Mitochondrial protein import | REACTOME | R-HSA-1268020 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37044213 | 2023 | NOX4-TIM23 interaction regulates NOX4 mitochondrial import and metabolic reprogramming. | 0 |
| 37044213 | 2023 | NOX4-TIM23 interaction regulates NOX4 mitochondrial import and metabolic reprogramming. | 0 |
| 32074073 | 2020 | From TOM to the TIM23 complex - handing over of a precursor. | 22 |
| 33197464 | 2020 | Mitochondrial Oxidative Stress Induces Rapid Intermembrane Space/Matrix Translocation of Apurinic/Apyrimidinic Endonuclease 1 Protein through TIM23 Complex. | 6 |
| 32074073 | 2020 | From TOM to the TIM23 complex - handing over of a precursor. | 22 |
| 33197464 | 2020 | Mitochondrial Oxidative Stress Induces Rapid Intermembrane Space/Matrix Translocation of Apurinic/Apyrimidinic Endonuclease 1 Protein through TIM23 Complex. | 6 |
| 31346086 | 2019 | Mutant huntingtin disrupts mitochondrial proteostasis by interacting with TIM23. | 37 |
| 31346086 | 2019 | Mutant huntingtin disrupts mitochondrial proteostasis by interacting with TIM23. | 37 |
| 29413900 | 2018 | Expression of the human TIMM23 and TIMM23B genes is regulated by the GABP transcription factor. | 3 |
| 29413900 | 2018 | Expression of the human TIMM23 and TIMM23B genes is regulated by the GABP transcription factor. | 3 |
| 27178215 | 2016 | Interaction of divalent metal ions with human translocase of inner membrane of mitochondria Tim23. | 0 |
| 27178215 | 2016 | Interaction of divalent metal ions with human translocase of inner membrane of mitochondria Tim23. | 0 |
| 24636990 | 2014 | Unraveling the intricate organization of mammalian mitochondrial presequence translocases: existence of multiple translocases for maintenance of mitochondrial function. | 24 |
| 25519239 | 2014 | Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders. | 15 |
| 24636990 | 2014 | Unraveling the intricate organization of mammalian mitochondrial presequence translocases: existence of multiple translocases for maintenance of mitochondrial function. | 24 |
Citation
Dessen P
TIMM23 (translocase of inner mitochondrial membrane 23)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/42566/timm23
