TIMP4 (TIMP metallopeptidase inhibitor 4)

2003-02-01  

Identity

HGNC
TIMP4
LOCATION
3p25.2
LOCUSID
7079
ALIAS
TIMP-4

Other Information

Locus ID:

NCBI: 7079
MIM: 601915
HGNC: 11823
Ensembl: ENSG00000157150

Variants:

dbSNP: 7079
ClinVar: 7079
TCGA: ENSG00000157150
COSMIC: TIMP4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000157150ENST00000287814Q99727

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
389151192024Altered brain expression and cerebrospinal fluid levels of TIMP4 in cerebral amyloid angiopathy.0
389151192024Altered brain expression and cerebrospinal fluid levels of TIMP4 in cerebral amyloid angiopathy.0
374952732023Contribution of gene polymorphisms on 3p25 to salivary gland carcinoma, ameloblastoma, and odontogenic keratocyst in the Chinese Han population.0
380692502023Defect of TIMP4 Is Associated with High Myopia and Participates in Rat Ocular Development in a Dose-Dependent Manner.0
374952732023Contribution of gene polymorphisms on 3p25 to salivary gland carcinoma, ameloblastoma, and odontogenic keratocyst in the Chinese Han population.0
380692502023Defect of TIMP4 Is Associated with High Myopia and Participates in Rat Ocular Development in a Dose-Dependent Manner.0
343790462022The Expression of Matrix Metalloproteinases in Eyes with Intraocular Lymphoma.1
343790462022The Expression of Matrix Metalloproteinases in Eyes with Intraocular Lymphoma.1
347818852021Comprehensive analysis of expression, prognosis and immune infiltration for TIMPs in glioblastoma.6
347818852021Comprehensive analysis of expression, prognosis and immune infiltration for TIMPs in glioblastoma.6
298634102019C>T (rs17035945) polymorphism of TIMP-4 protects against preeclampsia.1
308918262019Upregulated long noncoding RNA Linc00261 in pre-eclampsia and its effect on trophoblast invasion and migration via regulating miR-558/TIMP4 signaling pathway.23
310744902019The transition of tissue inhibitor of metalloproteinases from -4 to -1 induces aggressive behavior and poor patient survival in dedifferentiated liposarcoma via YAP/TAZ activation.7
313712662019Gene Expression in Intracranial Aneurysms-Comparison Analysis of Aneurysmal Walls and Extracranial Arteries with Real-Time Polymerase Chain Reaction and Immunohistochemistry.0
298634102019C>T (rs17035945) polymorphism of TIMP-4 protects against preeclampsia.1

Citation

Dessen P

TIMP4 (TIMP metallopeptidase inhibitor 4)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42574/deep-insight-explorer/gene-fusions-explorer/