Identity
HGNC
LOCATION
3q25.1
LOCUSID
ALIAS
H-L6,L6,M3S1,TAAL6
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4071
MIM: 191155
HGNC: 11853
Ensembl: ENSG00000169908
Variants:
dbSNP: 4071
ClinVar: 4071
TCGA: ENSG00000169908
COSMIC: TM4SF1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000169908 | ENST00000305366 | P30408 |
| ENSG00000169908 | ENST00000472441 | C9J611 |
| ENSG00000169908 | ENST00000493298 | F8WBG6 |
| ENSG00000169908 | ENST00000493348 | F8WF27 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38251858 | 2024 | Breast cancer malignancy is governed by regulation of the macroH2A2/TM4SF1 axis, the AKT/NF-κB pathway, and elevated MMP13 expression. | 0 |
| 38251858 | 2024 | Breast cancer malignancy is governed by regulation of the macroH2A2/TM4SF1 axis, the AKT/NF-κB pathway, and elevated MMP13 expression. | 0 |
| 36252184 | 2023 | Tm4sf1-marked Endothelial Subpopulation Is Dysregulated in Pulmonary Arterial Hypertension. | 2 |
| 37069693 | 2023 | TM4SF1 upregulates MYH9 to activate the NOTCH pathway to promote cancer stemness and lenvatinib resistance in HCC. | 2 |
| 36252184 | 2023 | Tm4sf1-marked Endothelial Subpopulation Is Dysregulated in Pulmonary Arterial Hypertension. | 2 |
| 37069693 | 2023 | TM4SF1 upregulates MYH9 to activate the NOTCH pathway to promote cancer stemness and lenvatinib resistance in HCC. | 2 |
| 35081723 | 2022 | Hyper-expression and hypomethylation of TM4SF1 are associated with lymph node metastases in papillary thyroid carcinoma patients. | 2 |
| 35532297 | 2022 | TM4SF1 promotes glioma malignancy through multiple mechanisms. | 1 |
| 35730016 | 2022 | Long Noncoding RNA BCYRN1 Recruits BATF to Promote TM4SF1 Upregulation and Enhance HCC Cell Proliferation and Invasion. | 4 |
| 35835740 | 2022 | TM4SF1 promotes esophageal squamous cell carcinoma metastasis by interacting with integrin α6. | 4 |
| 36274500 | 2022 | MicroRNA-501-3p targeting TM4SF1 facilitates tumor-related behaviors of gastric cancer cells via EMT signaling pathway. | 0 |
| 35081723 | 2022 | Hyper-expression and hypomethylation of TM4SF1 are associated with lymph node metastases in papillary thyroid carcinoma patients. | 2 |
| 35532297 | 2022 | TM4SF1 promotes glioma malignancy through multiple mechanisms. | 1 |
| 35730016 | 2022 | Long Noncoding RNA BCYRN1 Recruits BATF to Promote TM4SF1 Upregulation and Enhance HCC Cell Proliferation and Invasion. | 4 |
| 35835740 | 2022 | TM4SF1 promotes esophageal squamous cell carcinoma metastasis by interacting with integrin α6. | 4 |
Citation
Dessen P
TM4SF1 (transmembrane 4 L six family member 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/42583/tm4sf1
