Identity
HGNC
LOCATION
8p21.3
LOCUSID
ALIAS
CD263,DCR1,DCR1-TNFR,LIT,TRAIL-R3,TRAILR3,TRID
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8794
MIM: 603613
HGNC: 11906
Ensembl: ENSG00000173535
Variants:
dbSNP: 8794
ClinVar: 8794
TCGA: ENSG00000173535
COSMIC: TNFRSF10C
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000173535 | ENST00000356864 | O14798 |
| ENSG00000173535 | ENST00000517558 | E5RJI1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35226068 | 2023 | Hepatitis B Virus (HBV) Upregulates TRAIL-R3 Expression in Hepatocytes Resulting in Escape From Both Cell Apoptosis and Suppression of HBV Replication by TRAIL. | 1 |
| 35226068 | 2023 | Hepatitis B Virus (HBV) Upregulates TRAIL-R3 Expression in Hepatocytes Resulting in Escape From Both Cell Apoptosis and Suppression of HBV Replication by TRAIL. | 1 |
| 32111400 | 2020 | TRAIL receptors are differentially regulated and clinically significant in gallbladder cancer. | 3 |
| 32111400 | 2020 | TRAIL receptors are differentially regulated and clinically significant in gallbladder cancer. | 3 |
| 28420351 | 2017 | Prognostic significance of TRAIL-R3 and CCR-2 expression in tumor epithelial cells of patients with early breast cancer. | 9 |
| 28420351 | 2017 | Prognostic significance of TRAIL-R3 and CCR-2 expression in tumor epithelial cells of patients with early breast cancer. | 9 |
| 26050621 | 2016 | Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity. | 32 |
| 26542757 | 2016 | Epigenetic inactivation of TRAIL decoy receptors at 8p12-21.3 commonly deleted region confers sensitivity to Apo2L/trail-Cisplatin combination therapy in cervical cancer. | 11 |
| 26050621 | 2016 | Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity. | 32 |
| 26542757 | 2016 | Epigenetic inactivation of TRAIL decoy receptors at 8p12-21.3 commonly deleted region confers sensitivity to Apo2L/trail-Cisplatin combination therapy in cervical cancer. | 11 |
| 25808868 | 2015 | Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide. | 10 |
| 25808868 | 2015 | Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide. | 10 |
| 24534820 | 2014 | Does DcR1 (TNF-related apoptosis-inducing-ligand Receptor 3) have any role in human AMD pathogenesis? | 10 |
| 24649804 | 2014 | Membrane expression of trail receptors DcR1 and DcR2 in the normal endometrium, endometrial atypical hyperplasia and endometrioid endometrial cancer. | 0 |
| 24534820 | 2014 | Does DcR1 (TNF-related apoptosis-inducing-ligand Receptor 3) have any role in human AMD pathogenesis? | 10 |
Citation
Dessen P
TNFRSF10C (TNF receptor superfamily member 10c)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42607/tnfrsf10c
