Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8784
MIM: 603905
HGNC: 11914
Ensembl: ENSG00000186891
Variants:
dbSNP: 8784
ClinVar: 8784
TCGA: ENSG00000186891
COSMIC: TNFRSF18
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000186891 | ENST00000328596 | Q9Y5U5 |
| ENSG00000186891 | ENST00000379265 | Q9Y5U5 |
| ENSG00000186891 | ENST00000379268 | Q9Y5U5 |
| ENSG00000186891 | ENST00000486728 | J3KT02 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36155259 | 2023 | GITR Ligation Improves Anti-PD1-Mediated Restoration of Human MMR-Proficient Colorectal Carcinoma Tumor-Derived T Cells. | 5 |
| 36155259 | 2023 | GITR Ligation Improves Anti-PD1-Mediated Restoration of Human MMR-Proficient Colorectal Carcinoma Tumor-Derived T Cells. | 5 |
| 33122602 | 2022 | Phenotypic Changes of PD-1 and GITR in T Cells Are Associated With Hepatitis B Surface Antigen Seroclearance. | 4 |
| 34908008 | 2022 | DNA Methylation and mRNA Expression of OX40 (TNFRSF4) and GITR (TNFRSF18, AITR) in Head and Neck Squamous Cell Carcinoma Correlates With HPV Status, Mutational Load, an Interferon-γ Signature, Signatures of Immune Infiltrates, and Survival. | 6 |
| 33122602 | 2022 | Phenotypic Changes of PD-1 and GITR in T Cells Are Associated With Hepatitis B Surface Antigen Seroclearance. | 4 |
| 34908008 | 2022 | DNA Methylation and mRNA Expression of OX40 (TNFRSF4) and GITR (TNFRSF18, AITR) in Head and Neck Squamous Cell Carcinoma Correlates With HPV Status, Mutational Load, an Interferon-γ Signature, Signatures of Immune Infiltrates, and Survival. | 6 |
| 33280089 | 2021 | Experimental Medicine Study to Measure Immune Checkpoint Receptors PD-1 and GITR Turnover Rates In Vivo in Humans. | 1 |
| 33654081 | 2021 | Structures of mouse and human GITR-GITRL complexes reveal unique TNF superfamily interactions. | 10 |
| 34102305 | 2021 | Glucocorticoid induced TNF receptor family-related protein (GITR) - A novel driver of atherosclerosis. | 3 |
| 34589088 | 2021 | GITR Promotes the Polarization of TFH-Like Cells in Helicobacter pylori-Positive Gastritis. | 5 |
| 33280089 | 2021 | Experimental Medicine Study to Measure Immune Checkpoint Receptors PD-1 and GITR Turnover Rates In Vivo in Humans. | 1 |
| 33654081 | 2021 | Structures of mouse and human GITR-GITRL complexes reveal unique TNF superfamily interactions. | 10 |
| 34102305 | 2021 | Glucocorticoid induced TNF receptor family-related protein (GITR) - A novel driver of atherosclerosis. | 3 |
| 34589088 | 2021 | GITR Promotes the Polarization of TFH-Like Cells in Helicobacter pylori-Positive Gastritis. | 5 |
| 32259529 | 2020 | GITR shapes humoral immunity by controlling the balance between follicular T helper cells and regulatory T follicular cells. | 7 |
Citation
Dessen P
TNFRSF18 (TNF receptor superfamily member 18)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42617/tnfrsf18
