TNFRSF19 (TNF receptor superfamily member 19)

2003-05-01  

Identity

HGNC
TNFRSF19
LOCATION
13q12.12
LOCUSID
55504
ALIAS
TAJ,TAJ-alpha,TRADE,TROY

Other Information

Locus ID:

NCBI: 55504
MIM: 606122
HGNC: 11915
Ensembl: ENSG00000127863

Variants:

dbSNP: 55504
ClinVar: 55504
TCGA: ENSG00000127863
COSMIC: TNFRSF19

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000127863ENST00000248484Q9NS68
ENSG00000127863ENST00000382258Q9NS68
ENSG00000127863ENST00000382258A0A024RDM5
ENSG00000127863ENST00000382263Q9NS68
ENSG00000127863ENST00000403372Q9NS68

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Cytokine-cytokine receptor interactionKEGGhsa04060

References

Pubmed IDYearTitleCitations
380478072024TNFRSF19 within the 13q12.12 Risk Locus Functions as a Lung Cancer Suppressor by Binding Wnt3a to Inhibit Wnt/β-Catenin Signaling.0
380478072024TNFRSF19 within the 13q12.12 Risk Locus Functions as a Lung Cancer Suppressor by Binding Wnt3a to Inhibit Wnt/β-Catenin Signaling.0
353515232022Unique molecular characteristics of NAFLD-associated liver cancer accentuate β-catenin/TNFRSF19-mediated immune evasion.14
353545422022Long noncoding RNA SNHG8 promotes chemoresistance in gastric cancer via binding with hnRNPA1 and stabilizing TROY expression.5
353515232022Unique molecular characteristics of NAFLD-associated liver cancer accentuate β-catenin/TNFRSF19-mediated immune evasion.14
353545422022Long noncoding RNA SNHG8 promotes chemoresistance in gastric cancer via binding with hnRNPA1 and stabilizing TROY expression.5
343584532021Troy/Tnfrsf19 marks epidermal cells that govern interfollicular epidermal renewal and cornification.1
343584532021Troy/Tnfrsf19 marks epidermal cells that govern interfollicular epidermal renewal and cornification.1
321027522020Downregulation of TNFRSF19 and RAB43 by a novel miRNA, miR-HCC3, promotes proliferation and epithelial-mesenchymal transition in hepatocellular carcinoma cells.5
326291762020TROY signals through JAK1-STAT3 to promote glioblastoma cell migration and resistance.11
321027522020Downregulation of TNFRSF19 and RAB43 by a novel miRNA, miR-HCC3, promotes proliferation and epithelial-mesenchymal transition in hepatocellular carcinoma cells.5
326291762020TROY signals through JAK1-STAT3 to promote glioblastoma cell migration and resistance.11
303376862019TROY interacts with RKIP to promote glioma development.6
304757562019TROY expression is associated with pathological stage and poor prognosis in patients treated with radical cystectomy.1
305011442019Immunohistochemical Analysis of LGR5 and TROY Expression in Gastric Carcinogenesis Demonstrates an Inverse Trend.0

Citation

Dessen P

TNFRSF19 (TNF receptor superfamily member 19)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42618