TNR (tenascin R)

2003-05-01  

Identity

HGNC
TNR
LOCATION
1q25.1
LOCUSID
7143
ALIAS
TN-R
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7143
MIM: 601995
HGNC: 11953
Ensembl: ENSG00000116147

Variants:

dbSNP: 7143
ClinVar: 7143
TCGA: ENSG00000116147
COSMIC: TNR

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116147ENST00000263525Q92752
ENSG00000116147ENST00000367674Q92752
ENSG00000116147ENST00000422274H0Y668

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Focal adhesionKEGGko04510
ECM-receptor interactionKEGGko04512
Focal adhesionKEGGhsa04510
ECM-receptor interactionKEGGhsa04512
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206
Extracellular matrix organizationREACTOMER-HSA-1474244
ECM proteoglycansREACTOMER-HSA-3000178

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
305639842018A case-control genome-wide association study of ADHD discovers a novel association with the tenascin R (TNR) gene.7
305639842018A case-control genome-wide association study of ADHD discovers a novel association with the tenascin R (TNR) gene.7
265958082016Whole-Exome Sequencing in Familial Parkinson Disease.41
265958082016Whole-Exome Sequencing in Familial Parkinson Disease.41
261909822015A cross-species genetic analysis identifies candidate genes for mouse anxiety and human bipolar disorder.13
261909822015A cross-species genetic analysis identifies candidate genes for mouse anxiety and human bipolar disorder.13
232694782013Tenascins and inflammation in disorders of the nervous system.30
232694782013Tenascins and inflammation in disorders of the nervous system.30
209507962011Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area.20
214560202011Spatiotemporal distribution of tenascin-R in the developing human cerebral cortex parallels neuronal migration.8
209507962011Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area.20
214560202011Spatiotemporal distribution of tenascin-R in the developing human cerebral cortex parallels neuronal migration.8
202021252010KIAA0510, the 3'-untranslated region of the tenascin-R gene, and tenascin-R are overexpressed in pilocytic astrocytomas.8
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
204524822010Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.36

Citation

Dessen P

TNR (tenascin R)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42649