FCMR (Fc fragment of IgM receptor)

2003-11-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
FAIM3,TOSO
FUSION GENES

Other Information

Locus ID:

NCBI: 9214
MIM: 606015
HGNC: 14315
Ensembl: ENSG00000162894

Variants:

dbSNP: 9214
ClinVar: 9214
TCGA: ENSG00000162894
COSMIC: FCMR

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162894ENST00000367091O60667
ENSG00000162894ENST00000442471O60667
ENSG00000162894ENST00000463473E9PQG1
ENSG00000162894ENST00000525793E9PN59
ENSG00000162894ENST00000529560E9PMT7
ENSG00000162894ENST00000530505E9PPV1
ENSG00000162894ENST00000628511O60667

Expression (GTEx)

0
50
100
150
200
250
300

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
342099052021Differences between Human and Mouse IgM Fc Receptor (FcµR).5
342099052021Differences between Human and Mouse IgM Fc Receptor (FcµR).5
314499052020Mapping of the binding site for FcμR in human IgM-Fc.4
325729082020TGIF2 promotes cervical cancer metastasis by negatively regulating FCMR.6
327843342020TOSO interacts with SYK and enhances BCR pathway activation in chronic lymphocytic leukemia.1
314499052020Mapping of the binding site for FcμR in human IgM-Fc.4
325729082020TGIF2 promotes cervical cancer metastasis by negatively regulating FCMR.6
327843342020TOSO interacts with SYK and enhances BCR pathway activation in chronic lymphocytic leukemia.1
212645332012Overexpression of Fc mu receptor (FCMR, TOSO) gene in chronic lymphocytic leukemia patients.5
226752002012Toso, a functional IgM receptor, is regulated by IL-2 in T and NK cells.18
212645332012Overexpression of Fc mu receptor (FCMR, TOSO) gene in chronic lymphocytic leukemia patients.5
226752002012Toso, a functional IgM receptor, is regulated by IL-2 in T and NK cells.18
211337332011TOSO is overexpressed and correlated with disease progression in Chinese patients with chronic lymphocytic leukemia.5
216132572011Toso regulates the balance between apoptotic and nonapoptotic death receptor signaling by facilitating RIP1 ubiquitination.22
217568052011[Expression and prognostic significance of TOSO in CD19+ B cells from Chinese CLL patients].1

Citation

Dessen P

FCMR (Fc fragment of IgM receptor)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/42664/gene-fusions/css/favicon/apple-touch-icon.png