TRAM1 (translocation associated membrane protein 1)

2003-06-01  

Identity

HGNC
TRAM1
LOCATION
8q13.3
LOCUSID
23471
ALIAS
PNAS8,TRAM,TRAMP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23471
MIM: 605190
HGNC: 20568
Ensembl: ENSG00000067167

Variants:

dbSNP: 23471
ClinVar: 23471
TCGA: ENSG00000067167
COSMIC: TRAM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000067167ENST00000262213Q15629
ENSG00000067167ENST00000262213Q6FHL3
ENSG00000067167ENST00000518678E5RFP8
ENSG00000067167ENST00000521425G3XAN4

Expression (GTEx)

0
50
100
150
200
250
300
350
400
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Protein processing in endoplasmic reticulumKEGGko04141
Protein processing in endoplasmic reticulumKEGGhsa04141
Metabolism of proteinsREACTOMER-HSA-392499
TranslationREACTOMER-HSA-72766
SRP-dependent cotranslational protein targeting to membraneREACTOMER-HSA-1799339
Gene ExpressionREACTOMER-HSA-74160

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
377680832023The REEP5/TRAM1 complex binds SARS-CoV-2 NSP3 and promotes virus replication.1
377680832023The REEP5/TRAM1 complex binds SARS-CoV-2 NSP3 and promotes virus replication.1
347643602021The human TRAM1 locus expresses circular RNAs.1
347938332021Identification of TRAMs as sphingolipid-binding proteins using a photoactivatable and clickable short-chain ceramide analog.3
347643602021The human TRAM1 locus expresses circular RNAs.1
347938332021Identification of TRAMs as sphingolipid-binding proteins using a photoactivatable and clickable short-chain ceramide analog.3
256008072015TRAM1 protect HepG2 cells from palmitate induced insulin resistance through ER stress-JNK pathway.9
256008072015TRAM1 protect HepG2 cells from palmitate induced insulin resistance through ER stress-JNK pathway.9
203313782010Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.30
204069642010Risk of meningioma and common variation in genes related to innate immunity.21
204387852010Polymorphisms in innate immunity genes and risk of childhood leukemia.12
205883082010Dengue hemorrhagic fever is associated with polymorphisms in JAK1.12
203313782010Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.30
204069642010Risk of meningioma and common variation in genes related to innate immunity.21
204387852010Polymorphisms in innate immunity genes and risk of childhood leukemia.12

Citation

Dessen P

TRAM1 (translocation associated membrane protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42689/js/template.js