TRPM5 (transient receptor potential cation channel subfamily M member 5)

2003-02-01  

Identity

HGNC
TRPM5
LOCATION
11p15.5
LOCUSID
29850
ALIAS
LTRPC5,MTR1

Other Information

Locus ID:

NCBI: 29850
MIM: 604600
HGNC: 14323
Ensembl: ENSG00000070985

Variants:

dbSNP: 29850
ClinVar: 29850
TCGA: ENSG00000070985
COSMIC: TRPM5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000070985ENST00000155858Q9NZQ8
ENSG00000070985ENST00000528453E9PQF7
ENSG00000070985ENST00000533060E9PRW0
ENSG00000070985ENST00000533881A0A0C4DGF4

Expression (GTEx)

0
1
2
3
4
5
6
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Taste transductionKEGGko04742
Taste transductionKEGGhsa04742
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Ion channel transportREACTOMER-HSA-983712
Stimuli-sensing channelsREACTOMER-HSA-2672351
TRP channelsREACTOMER-HSA-3295583

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
347671452022Association of TRPM5 Asn235Ser Polymorphism and Trace Elements/Minerals in Chronic Gastritis Patients: a Case-Control Study.1
347671452022Association of TRPM5 Asn235Ser Polymorphism and Trace Elements/Minerals in Chronic Gastritis Patients: a Case-Control Study.1
337739862021Hair Follicle Chemosensation: TRPM5 Signaling Is Required for Anagen Maintenance.2
339790162021Novel association between a transient receptor potential cation channel subfamily M member 5 expression quantitative trait locus rs35197079 and decreased susceptibility of gestational diabetes mellitus in a Chinese population.1
337739862021Hair Follicle Chemosensation: TRPM5 Signaling Is Required for Anagen Maintenance.2
339790162021Novel association between a transient receptor potential cation channel subfamily M member 5 expression quantitative trait locus rs35197079 and decreased susceptibility of gestational diabetes mellitus in a Chinese population.1
325212532020TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes.8
325212532020TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes.8
283667702017A bio-cultural approach to the study of food choice: The contribution of taste genetics, population and culture.16
283667702017A bio-cultural approach to the study of food choice: The contribution of taste genetics, population and culture.16
259677132015Role of the transient receptor potential (TRP) channel gene expressions and TRP melastatin (TRPM) channel gene polymorphisms in obesity-related metabolic syndrome.13
265465342015Association of TRPM Channel Gene Polymorphisms with Systemic Sclerosis.7
265714002015GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.71
259677132015Role of the transient receptor potential (TRP) channel gene expressions and TRP melastatin (TRPM) channel gene polymorphisms in obesity-related metabolic syndrome.13
265465342015Association of TRPM Channel Gene Polymorphisms with Systemic Sclerosis.7

Citation

Dessen P

TRPM5 (transient receptor potential cation channel subfamily M member 5)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42708